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Implements standard and reference based multiple imputation methods for continuous longitudinal endpoints (Gower-Page et al. (2022) <doi:10.21105/joss.04251>). In particular, this package supports deterministic conditional mean imputation and jackknifing as described in Wolbers et al. (2022) <doi:10.1002/pst.2234>, Bayesian multiple imputation as described in Carpenter et al. (2013) <doi:10.1080/10543406.2013.834911>, and bootstrapped maximum likelihood imputation as described in von Hippel and Bartlett (2021) <doi:10.1214/20-STS793>.
Version: | 1.2.6 |
Depends: | R (≥ 3.4.0) |
Imports: | mmrm, pkgload, Matrix, methods, Rcpp (≥ 0.12.0), RcppParallel (≥ 5.0.1), rstan (≥ 2.26.0), rstantools (≥ 2.1.1), R6, assertthat |
LinkingTo: | BH (≥ 1.66.0), Rcpp (≥ 0.12.0), RcppEigen (≥ 0.3.3.3.0), RcppParallel (≥ 5.0.1), rstan (≥ 2.26.0), StanHeaders (≥ 2.26.0) |
Suggests: | dplyr, tidyr, nlme, testthat, emmeans, tibble, mvtnorm, knitr, rmarkdown, bookdown, lubridate, purrr, ggplot2, R.rsp |
Published: | 2023-11-24 |
DOI: | 10.32614/CRAN.package.rbmi |
Author: | Craig Gower-Page [aut, cre], Alessandro Noci [aut], Marcel Wolbers [ctb], Roche [cph, fnd] |
Maintainer: | Craig Gower-Page <craig.gower-page at roche.com> |
BugReports: | https://github.com/insightsengineering/rbmi/issues |
License: | Apache License (≥ 2) |
URL: | https://insightsengineering.github.io/rbmi/, https://github.com/insightsengineering/rbmi |
NeedsCompilation: | yes |
SystemRequirements: | GNU make |
Materials: | README NEWS |
In views: | ClinicalTrials |
CRAN checks: | rbmi results |
Reference manual: | rbmi.pdf |
Vignettes: |
rbmi: Advanced Functionality rbmi: Quickstart rbmi: Statistical Specifications |
Package source: | rbmi_1.2.6.tar.gz |
Windows binaries: | r-devel: rbmi_1.2.6.zip, r-release: rbmi_1.2.6.zip, r-oldrel: rbmi_1.2.6.zip |
macOS binaries: | r-release (arm64): rbmi_1.2.6.tgz, r-oldrel (arm64): rbmi_1.2.6.tgz, r-release (x86_64): rbmi_1.2.6.tgz, r-oldrel (x86_64): rbmi_1.2.6.tgz |
Old sources: | rbmi archive |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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