gsDesign: Group Sequential Design

Derives group sequential clinical trial designs and describes their properties. Particular focus on time-to-event, binary, and continuous outcomes. Largely based on methods described in Jennison, Christopher and Turnbull, Bruce W., 2000, "Group Sequential Methods with Applications to Clinical Trials" ISBN: 0-8493-0316-8.

Version:	3.6.2
Depends:	R (≥ 3.5.0)
Imports:	dplyr (≥ 1.1.0), ggplot2 (≥ 3.1.1), graphics, gt, magrittr, methods, r2rtf, rlang, stats, tibble, tidyr, tools, xtable
Suggests:	covr, gridExtra, kableExtra, knitr, mvtnorm, ragg, rmarkdown, scales, testthat, utils
Published:	2024-04-09
Author:	Keaven Anderson [aut, cre]
Maintainer:	Keaven Anderson <keaven_anderson at merck.com>
BugReports:	https://github.com/keaven/gsDesign/issues
License:	GPL (≥ 3)
Copyright:	Copyright 2010, Merck Research Laboratories
URL:	https://keaven.github.io/gsDesign/, https://github.com/keaven/gsDesign
NeedsCompilation:	yes
Materials:	README NEWS
In views:	ExperimentalDesign
CRAN checks:	gsDesign results

Documentation:

Reference manual:

gsDesign.pdf

Vignettes:

Conditional Power and Conditional Error A gentle introduction to group sequential design Graphical testing for group sequential design A Cure Model Calendar-Based Design Spending function overview Overview of survival endpoint design Vaccine Efficacy Trial Design Binomial SPRT gsDesign package overview Basic time-to-event group sequential design using gsSurv Multiplicity graphs Two-sample normal sample size Integer sample size and event counts

Downloads:

Package source:	gsDesign_3.6.2.tar.gz
Windows binaries:	r-devel: gsDesign_3.6.2.zip, r-release: gsDesign_3.6.2.zip, r-oldrel: gsDesign_3.6.2.zip
macOS binaries:	r-release (arm64): gsDesign_3.6.2.tgz, r-oldrel (arm64): gsDesign_3.6.2.tgz, r-release (x86_64): gsDesign_3.6.2.tgz, r-oldrel (x86_64): gsDesign_3.6.2.tgz
Old sources:	gsDesign archive

Reverse dependencies:

Reverse depends:	gsbDesign
Reverse imports:	BayesOrdDesign, gsDesign2, randomizeR
Reverse suggests:	ADCT, gMCPLite, gscounts, ph2bye, ph2mult, RTSA, simtrial

Linking:

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