The hardware and bandwidth for this mirror is donated by dogado GmbH, the Webhosting and Full Service-Cloud Provider. Check out our Wordpress Tutorial.
If you wish to report a bug, or if you are interested in having us mirror your free-software or open-source project, please feel free to contact us at mirror[@]dogado.de.

gsDesign 3.6.3 (July, 2024)

New features

• Implemented conditional error spending functions sfXG1(), sfXG2(), and sfXG3() based on Xi and Gallo (2019). See vignette("ConditionalErrorSpending") for details and reproduced examples from the literature (@keaven, #147. Thanks, @xidongdxi, for comments on vignette).

Improvements

• Enhanced eEvents() with input validation to ensure lambda is not NULL (@keaven, 97f629d).

Testing

• Added independent testing for gsSurvCalendar() (@myeongjong, #144).
• Expanded test coverage for gsBinomialExact() (@menglu2, #143).

gsDesign 3.6.2 (April, 2024)

Documentation

• Add new vignette on conditional power and conditional error, see vignette("ConditionalPowerPlot") (beb2957, 727fe20, 57394fe).
• Fix roxygen2 warning and use magrittr pipes in vignette for consistency (#131).

Testing

• Move independently programmed functions for validation as standard test helper files (#130).

gsDesign 3.6.1 (February, 2024)

New features

• gsBoundSummary() now has the as_rtf() method implemented to generate RTF outputs for bound summary tables (@wangben718, #107).
• plotgsPower() gets new arguments offset and titleAnalysisLegend to enable more flexible and accurate power plots (plottype = 2) (@jdblischak, #121, #123).

Improvements

• The plotting functions now use dplyr::reframe() to replace dplyr::summarize() when performing grouped cumsum() (@jdblischak, #114).
• The plotting functions are updated to use the .data pronoun from rlang with ggplot2::aes(). This simplifies the code and follows the recommended practice when using ggplot2 in packages (@jdblischak, #124).
• hGraph() now uses named guide argument in the scale_fill_manual() call to be compatible with ggplot2 3.5.0 (@teunbrand, #115). Note: this function has been deprecated and moved to gMCPLite since gsDesign 3.4.0. It will be removed from gsDesign in a future version. Please use gMCPLite::hGraph() instead.

Documentation

• vignettes("SurvivalOverview") is updated with more details and minor corrections (@keaven, #126).
• Fix equation syntax in plotting function documentation to render math symbols properly (@keaven, #118).

gsDesign 3.6.0 (November, 2023)

Breaking changes

• gsSurv() and nSurv() have updated default values for T and minfup so that function calls with no arguments will run. Legacy code with T or minfup not explicitly specified could break (#105).

New features

• gsSurvCalendar() function added to enable group sequential design for time-to-event outcomes using calendar timing of interim analysis specification (#105).
• as_rtf() method for gsBinomialExact() objects added, enable RTF table outputs for standard word processing software (#102).

Improvements

• toBinomialExact() and gsBinomialExact(): fix error checking in bound computations, improve documentation and error messages (#105).
• print.gsSurv(): Improve the display of targeted events (very minor). The boundary crossing probability computations did not change. The need is made evident by the addition of the toInteger() function (#105).
• toInteger(): Fix the documentation and execution based on the ratio argument (#105).
• Update the vaccine efficacy, Poisson mixture model, and toInteger vignettes (#105).
• Standardize and improve roxygen2 documentation (#104).

gsDesign 3.5.0 (July, 2023)

• sfPower() now allows a wider parameter range (0, 15].
• toInteger() function added to convert gsDesign or gsSurv classes to integer sample size and event counts.
• toBinomialExact() function added to convert time-to-event bounds to exact binomial for low event rate studies.
• Added “A Gentle Introduction to Group Sequential Design” vignette for an introduction to asymptotics for group sequential design.
• as_table() and as_gt() methods for gsBinomialExact objects added, as described in the new “Binomial SPRT” vignette.
• In plot.ssrCP(), the hat syntax in the mathematical expression is revised, resolving labeling issues.
• ggplot2::qplot() usage replaced due to its deprecation in ggplot2 3.4.0.
• Link update for the gsDesign manual in the documentation, now directly pointing to the gsDesign technical manual bookdown project.
• Introduced a new hex sticker logo.

gsDesign 3.4.0 (October, 2022)

• Removed restriction on gsCP() interim test statistic zi (#63).
• Removed gMCP dependency. Updated vignettes and linked to vignettes in gMCPLite (#69).
• Added deprecation warning to hGraph() and suggested using gMCPLite::hGraph() instead (#70).
• Moved ggplot2 from Depends to Imports (#56).

gsDesign 3.3.0 (May, 2022)

• Addition of vignettes
  • Demonstrate cure model and calendar-based analysis timing for time-to-event endpoint design
  • Vaccine efficacy design using spending bounds and exact binomial boundary crossing probabilities
• Minor fix to labeling in print.gsProbability
• Fixed error in sfStep
• Updates to reduce R CMD check and other minor issues

gsDesign 3.2.2 (January, 2022)

• Use inherits() instead of is() to determine if an object is an instance of a class, when appropriate
• Correctly close graphics device in unit tests to avoid plot output file not found issues
• Minor fixes to hGraph() for multiplicity graphs
• Minor fix to nBinomial() when odds-ratio scale specified to resolve user issue
• Minor changes to vignettes

gsDesign 3.2.1 (July, 2021)

• Changed gt package usage in a vignette due to deprecated gt function
• Replied to minor comments from CRAN reviewer (no functionality impact)
• Minor update to DESCRIPTION citing Jennison and Turnbull reference

gsDesign 3.2.0 (January, 2021)

• Substantially updated unit testing to increase code coverage above 80%
• Updated error checking messages to print function where check fails
• Removed dependencies on plyr packages
• Updated github actions

gsDesign 3.1.1 (May, 2020)

• Vignettes updated
• Added hGraph() to support ggplot2 versions of multiplicity graphs
• Eliminated unnecessary check from sequentialPValue
• Targeted release to CRAN
• Removed dependencies on reshape2, plyr
• Updated continuous integration
• Updated license

gsDesign 3.1.0 (April, 2019)

• Addition of pkgdown web site
• Updated unit testing to from RUnit to testthat
• Converted to roxygen2 generation of help files
• Converted vignettes to R Markdown
• Added Travis-CI and Appveyor support
• Added sequentialPValue function
• Backwards compatible addition of spending time capabilities to gsDesign and gsSurv

gsDesign 3.0-5 (January, 2018)

• Registered C routines
• Fixed “gsbound”
• Replaced “array” by “rep” calls to avoid R CMD check warnings

gsDesign 3.0-4 (September, 2017)

• First Github-based release
• Cleaned up documentation for nBinomial1Sample()
• Updated documentation and code (including one default value for an argument) for nBinomial1Sample() to improve error handling and clarity
• Updated sfLDOF() to generalize with rho parameter; still backwards compatible for Lan-DeMets O’Brien-Fleming

gsDesign 3.0-3

• Introduced spending time as a separate concept from information time to enable concepts such as calendar-based spending functions. The only user function changed is the gsDesign() function and the change is the addition of the parameters usTime and lsTime; default behavior is backwards compatible.

gsDesign 3.0-2 (February, 2016)

• Simplified conditional power section of gsDesignManual.pdf in doc directory
• Corrected basic calculation in gsCP()
• Eliminated deprecated ggplot2 function opts()

gsDesign 3.0-1 (January, 2016)

• More changes to comply with R standards (in NAMESPACE - importFrom statements - and DESCRIPTION - adding plyr to imports) ensuring appropriate references.
• Deleted link in documentation that no longer exists (gsBinomialExact.Rd).
• Last planned RForge-based release; moving to Github.

gsDesign 3.0-0 (December, 2015)

• Updated xtable extension to meet R standards for extensions.
• Fixed xtable.gsSurv and print.gsSurv to work with 1-sided designs
• Update to calls to ggplot to replace show_guide (deprecated) with show.legend arguments where used in ggplot2::geom_text calls; no user impact
• Minor typo fixed in sfLogistic help file
• Cleaned up “imports” and “depends” in an effort to be an R “good citizen”
• Registered S3 methods in NAMESPACE

gsDesign 2.9-4

• Minor edit to package description to comply with R standards

gsDesign 2.9-3 (November, 2014)

• Added sfTrimmed as likely preferred spending function approach to skipping early or all interim efficacy analyses; this also can adjust bound when final analysis is performed with less than maximum planned information. Updated help(sfTrimmed) to demonstrate these capabilities.
• Added sfGapped, which is primarily intended to eliminate futility analyses later in a study; see help(sfGapped) for an example
• Added summary.spendfn() to provide textual summary of spending functions; this simplified the print function for gsDesign objects
• Added sfStep() which can be used to set an interim spend when the exact amount of information is unknown; an example of how this can be misused is provided in the help file
• Fixed rounding so that gsBoundSummary, xtable.gsSurv and summary.gsDesign are consistent for gsSurv objects

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
Health stats visible at Monitor.