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easyEWAS: Perform and Visualize EWAS Analysis

Tools for conducting epigenome-wide association studies (EWAS) and visualizing results. Users provide sample metadata and methylation matrices to run EWAS with linear models, linear mixed-effects models, or Cox models. The package supports downstream visualization, bootstrap validation, enrichment analysis, batch effect correction, and differentially methylated region (DMR) analysis with optional parallel computing. Methods are described in Wang et al. (2025) <doi:10.1093/bioadv/vbaf026>, Johnson et al. (2007) <doi:10.1093/biostatistics/kxj037>, and Peters et al. (2015) <doi:10.1186/1756-8935-8-6>.

Version: 1.0.1
Depends: R (≥ 4.4.0)
Imports: R6, boot, CMplot, ddpcr, doParallel, dplyr, foreach, lmerTest, magrittr, parallel, readxl, survival, tictoc, vroom, withr, R.utils, lubridate
Suggests: AnnotationHub, ExperimentHub, DMRcate, sva, BiocParallel, clusterProfiler, enrichplot, org.Hs.eg.db, knitr, rmarkdown
Published: 2026-03-16
DOI: 10.32614/CRAN.package.easyEWAS
Author: Yuting Wang [aut, cre], Xu Gao [aut]
Maintainer: Yuting Wang <ytwang at pku.edu.cn>
BugReports: https://github.com/ytwangZero/easyEWAS/issues
License: GPL (≥ 3)
URL: https://github.com/ytwangZero/easyEWAS, https://easyewas-tutorial.github.io/
NeedsCompilation: no
CRAN checks: easyEWAS results

Documentation:

Reference manual: easyEWAS.html , easyEWAS.pdf

Downloads:

Package source: easyEWAS_1.0.1.tar.gz
Windows binaries: r-devel: easyEWAS_1.0.1.zip, r-release: easyEWAS_1.0.1.zip, r-oldrel: easyEWAS_1.0.1.zip
macOS binaries: r-release (arm64): easyEWAS_1.0.1.tgz, r-oldrel (arm64): easyEWAS_1.0.1.tgz, r-release (x86_64): easyEWAS_1.0.1.tgz, r-oldrel (x86_64): easyEWAS_1.0.1.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=easyEWAS to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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