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LSJM: Estimate Location-Scale Joint Models

Estimation of mixed models including a subject-specific variance that can be time- and covariate-dependent or defined for within- and between-visit variability. In the joint modeling framework, the package handles left truncation, interval censoring, and multistate models, and allows a flexible dependence structure between competing events and the longitudinal marker. Estimation is performed in a frequentist framework using the Marquardt-Levenberg algorithm. Methods are described in Courcoul et al. (2025) <doi:10.1002/sim.70244> and in Courcoul et al. (2026) <doi:10.1002/bimj.70123>.

Version: 0.1.0
Depends: R (≥ 3.5.0)
Imports: Rcpp, marqLevAlg, survival, flexsurv, ggplot2, splines, spacefillr, survminer, foreach, doParallel, SmoothHazard, parallel, mvtnorm, dplyr
LinkingTo: Rcpp, RcppArmadillo
Published: 2026-08-04
DOI: 10.32614/CRAN.package.LSJM (may not be active yet)
Author: Léonie Courcoul [aut, cre], Antoine Barbieri [aut], Hélène Jacqmin-Gadda [aut]
Maintainer: Léonie Courcoul <courcoul.leonie498 at gmail.com>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: yes
Materials: README, NEWS
CRAN checks: LSJM results

Documentation:

Reference manual: LSJM.html , LSJM.pdf

Downloads:

Package source: LSJM_0.1.0.tar.gz
Windows binaries: r-devel: not available, r-release: LSJM_0.1.0.zip, r-oldrel: LSJM_0.1.0.zip
macOS binaries: r-release (arm64): LSJM_0.1.0.tgz, r-oldrel (arm64): LSJM_0.1.0.tgz, r-release (x86_64): LSJM_0.1.0.tgz, r-oldrel (x86_64): LSJM_0.1.0.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=LSJM to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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