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Provides a comprehensive suite of genome-wide association study (GWAS) methods specifically designed for biobank-scale data. The package offers computationally efficient and robust association tests for time-to-event traits (e.g., Bi et al. (2020) <doi:10.1016/j.ajhg.2020.06.003>), ordinal categorical traits (e.g., Bi et al. (2021) <doi:10.1016/j.ajhg.2021.03.019>), and longitudinal traits (Xu et al. (2025) <doi:10.1038/s41467-025-56669-1>). Additionally, it includes functions for simulating genotype and phenotype data to support research and method development.
| Version: | 0.2.1 |
| Depends: | R (≥ 3.5.0) |
| Imports: | dplyr, data.table, mvtnorm, Matrix, RSQLite, lme4, ordinal, survival, Rcpp, RcppParallel, igraph |
| LinkingTo: | Rcpp, RcppArmadillo, RcppParallel, BH |
| Suggests: | dbplyr, optparse, tidyr, R.utils, SKAT |
| Published: | 2025-07-25 |
| DOI: | 10.32614/CRAN.package.GRAB |
| Author: | Wenjian Bi [aut], Wei Zhou [aut], Rounak Dey [aut], Zhangchen Zhao [aut], Seunggeun Lee [aut], Woody Miao [cre] |
| Maintainer: | Woody Miao <miaolin at pku.edu.cn> |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | yes |
| Materials: | README |
| CRAN checks: | GRAB results |
| Reference manual: | GRAB.html , GRAB.pdf |
| Package source: | GRAB_0.2.1.tar.gz |
| Windows binaries: | r-devel: not available, r-release: GRAB_0.2.1.zip, r-oldrel: not available |
| macOS binaries: | r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): GRAB_0.2.1.tgz, r-oldrel (x86_64): GRAB_0.2.1.tgz |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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