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CB2: CRISPR Pooled Screen Analysis using Beta-Binomial Test

Provides functions for hit gene identification and quantification of sgRNA (single-guided RNA) abundances for CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) pooled screen data analysis. Details are in Jeong et al. (2019) <doi:10.1101/gr.245571.118> and Baggerly et al. (2003) <doi:10.1093/bioinformatics/btg173>.

Version: 1.3.4
Depends: R (≥ 3.5.0)
Imports: Rcpp (≥ 0.12.16), metap, magrittr, dplyr, tibble, stringr, ggplot2, tidyr, glue, pheatmap, tools, readr, parallel, R.utils
LinkingTo: Rcpp, RcppArmadillo
Suggests: testthat, knitr, rmarkdown
Published: 2020-07-24
DOI: 10.32614/CRAN.package.CB2
Author: Hyun-Hwan Jeong [aut, cre]
Maintainer: Hyun-Hwan Jeong <jeong.hyunhwan at gmail.com>
License: MIT + file LICENSE
NeedsCompilation: yes
Materials: README
In views: Omics
CRAN checks: CB2 results

Documentation:

Reference manual: CB2.pdf
Vignettes: Handling the input matrix in CB2
CB2 Tutorial

Downloads:

Package source: CB2_1.3.4.tar.gz
Windows binaries: r-devel: CB2_1.3.4.zip, r-release: CB2_1.3.4.zip, r-oldrel: CB2_1.3.4.zip
macOS binaries: r-release (arm64): CB2_1.3.4.tgz, r-oldrel (arm64): CB2_1.3.4.tgz, r-release (x86_64): CB2_1.3.4.tgz, r-oldrel (x86_64): CB2_1.3.4.tgz
Old sources: CB2 archive

Linking:

Please use the canonical form https://CRAN.R-project.org/package=CB2 to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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