xlink: Genetic Association Models for X-Chromosome SNPS on Continuous, Binary and Survival Outcomes

The expression of X-chromosome undergoes three possible biological processes: X-chromosome inactivation (XCI), escape of the X-chromosome inactivation (XCI-E),and skewed X-chromosome inactivation (XCI-S). To analyze the X-linked genetic association for phenotype such as continuous, binary, and time-to-event outcomes with the actual process unknown, we propose a unified approach of maximizing the likelihood or partial likelihood over all of the potential biological processes. The methods are described in Wei Xu, Meiling Hao (2017) <doi:10.1002/gepi.22097>. And also see Dongxiao Han, Meiling Hao, Lianqiang Qu, Wei Xu (2019) <doi:10.1177/0962280219859037>.

Version:	1.0.1
Depends:	R (≥ 3.1.0)
Imports:	survival (≥ 2.41.3)
Suggests:	knitr, rmarkdown, testthat
Published:	2019-08-20
DOI:	10.32614/CRAN.package.xlink
Author:	Wei Xu [aut], Meiling Hao [aut], Yi Zhu [cre]
Maintainer:	Yi Zhu <yizhu87 at gmail.com>
BugReports:	https://github.com/qiuanzhu/xlink/issues
License:	GPL-2
URL:	https://github.com/qiuanzhu/xlink
NeedsCompilation:	no
Materials:	NEWS
CRAN checks:	xlink results

Documentation:

Reference manual:	xlink.pdf
Vignettes:	An Introduction to xlink

Downloads:

Package source:	xlink_1.0.1.tar.gz
Windows binaries:	r-devel: xlink_1.0.1.zip, r-release: xlink_1.0.1.zip, r-oldrel: xlink_1.0.1.zip
macOS binaries:	r-release (arm64): xlink_1.0.1.tgz, r-oldrel (arm64): xlink_1.0.1.tgz, r-release (x86_64): xlink_1.0.1.tgz, r-oldrel (x86_64): xlink_1.0.1.tgz
Old sources:	xlink archive

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