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The algorithm implemented in this package was designed to quickly estimates the distribution of the log-rank especially for heavy unbalanced groups. VALORATE estimates the null distribution and the p-value of the log-rank test based on a recent formulation. For a given number of alterations that define the size of survival groups, the estimation involves a weighted sum of distributions that are conditional on a co-occurrence term where mutations and events are both present. The estimation of conditional distributions is quite fast allowing the analysis of large datasets in few minutes <http://bioinformatica.mty.itesm.mx/valorate>.
| Version: | 1.0-1 |
| Depends: | R (≥ 3.1.0), methods |
| Imports: | survival, graphics, utils, stats |
| Published: | 2016-10-09 |
| DOI: | 10.32614/CRAN.package.valorate |
| Author: | Victor Trevino [aut, cre] |
| Maintainer: | Victor Trevino <vtrevino at itesm.mx> |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| URL: | http://bioinformatica.mty.itesm.mx/valorate |
| NeedsCompilation: | yes |
| CRAN checks: | valorate results |
| Reference manual: | valorate.pdf |
| Package source: | valorate_1.0-1.tar.gz |
| Windows binaries: | r-devel: valorate_1.0-1.zip, r-release: valorate_1.0-1.zip, r-oldrel: valorate_1.0-1.zip |
| macOS binaries: | r-release (arm64): valorate_1.0-1.tgz, r-oldrel (arm64): valorate_1.0-1.tgz, r-release (x86_64): valorate_1.0-1.tgz, r-oldrel (x86_64): valorate_1.0-1.tgz |
| Old sources: | valorate archive |
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