springer: Sparse Group Variable Selection for Gene-Environment Interactions in the Longitudinal Study

Recently, regularized variable selection has emerged as a powerful tool to identify and dissect gene-environment interactions. Nevertheless, in longitudinal studies with high dimensional genetic factors, regularization methods for G×E interactions have not been systematically developed. In this package, we provide the implementation of sparse group variable selection, based on both the quadratic inference function (QIF) and generalized estimating equation (GEE), to accommodate the bi-level selection for longitudinal G×E studies with high dimensional genomic features. Alternative methods conducting only the group or individual level selection have also been included. The core modules of the package have been developed in C++.

Version:	0.1.9
Depends:	R (≥ 3.5.0)
Imports:	MASS, Rcpp
LinkingTo:	Rcpp, RcppArmadillo
Published:	2024-02-01
DOI:	10.32614/CRAN.package.springer
Author:	Fei Zhou, Yuwen Liu, Xi Lu, Jie Ren, Cen Wu
Maintainer:	Fei Zhou <fei.zhou at outlook.com>
BugReports:	https://github.com/feizhoustat/springer/issues
License:	GPL-2
URL:	https://github.com/feizhoustat/springer
NeedsCompilation:	yes
Materials:	README NEWS
CRAN checks:	springer results

Documentation:

Reference manual:

springer.pdf

Downloads:

Package source:	springer_0.1.9.tar.gz
Windows binaries:	r-devel: springer_0.1.9.zip, r-release: springer_0.1.9.zip, r-oldrel: springer_0.1.9.zip
macOS binaries:	r-release (arm64): springer_0.1.9.tgz, r-oldrel (arm64): springer_0.1.9.tgz, r-release (x86_64): springer_0.1.9.tgz, r-oldrel (x86_64): springer_0.1.9.tgz
Old sources:	springer archive

Linking:

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