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The focus is on simulating and modeling families with founders drawn from a structured population (for example, with different ancestries or other potentially non-family relatedness), in contrast to traditional pedigree analysis that treats all founders as equally unrelated. Main function simulates a random pedigree for many generations, avoiding close relatives, pairing closest individuals according to a 1D geography and their randomly-drawn sex, and with variable children sizes to result in a target population size per generation. Auxiliary functions calculate kinship matrices, admixture matrices, and draw random genotypes across arbitrary pedigree structures starting from the corresponding founder values. The code is built around the plink FAM table format for pedigrees. Described in Yao and Ochoa (2022) <doi:10.1101/2022.03.25.485885>.
Version: | 1.1.6 |
Depends: | R (≥ 2.10) |
Imports: | Rcpp, stats, tibble |
LinkingTo: | Rcpp |
Suggests: | testthat (≥ 3.0.0), popkin, bnpsd (≥ 1.3.2), kinship2, RColorBrewer, knitr, rmarkdown |
Published: | 2023-01-09 |
DOI: | 10.32614/CRAN.package.simfam |
Author: | Alejandro Ochoa |
Maintainer: | Alejandro Ochoa <alejandro.ochoa at duke.edu> |
BugReports: | https://github.com/OchoaLab/simfam/issues |
License: | GPL (≥ 3) |
URL: | https://github.com/OchoaLab/simfam |
NeedsCompilation: | yes |
Materials: | README NEWS |
CRAN checks: | simfam results |
Reference manual: | simfam.pdf |
Vignettes: |
'simfam': simulate and model family pedigrees with structured founders |
Package source: | simfam_1.1.6.tar.gz |
Windows binaries: | r-devel: simfam_1.1.6.zip, r-release: simfam_1.1.6.zip, r-oldrel: simfam_1.1.6.zip |
macOS binaries: | r-release (arm64): simfam_1.1.6.tgz, r-oldrel (arm64): simfam_1.1.6.tgz, r-release (x86_64): simfam_1.1.6.tgz, r-oldrel (x86_64): simfam_1.1.6.tgz |
Old sources: | simfam archive |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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