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When multiple Cox proportional hazard models are performed on clinical data (month or year and status) and a set of differential expressions of genes, the results (Hazard risks, z-scores and p-values) can be used to create gene-expression signatures. Weights are calculated using the survival p-values of genes and are utilized to calculate expression values of the signature across the selected genes in all patients in a cohort. A Single or multiple univariate or multivariate Cox proportional hazard survival analyses of the patients in one cohort can be performed by using the gene-expression signature and visualized using our survival plots.
Version: | 1.0.0 |
Depends: | R (≥ 3.5.0) |
Imports: | stats, utils, graphics, grDevices, dplyr, forestplot, gplots, gtools, survival, survminer, ggplot2 |
Suggests: | Rmisc |
Published: | 2023-07-19 |
DOI: | 10.32614/CRAN.package.signatureSurvival |
Author: | Yuan-De Tan [aut, cre], Yuguang Ban [ctb] |
Maintainer: | Yuan-De Tan <tanyuande at gmail.com> |
License: | GPL (≥ 3) |
NeedsCompilation: | no |
CRAN checks: | signatureSurvival results |
Reference manual: | signatureSurvival.pdf |
Package source: | signatureSurvival_1.0.0.tar.gz |
Windows binaries: | r-devel: signatureSurvival_1.0.0.zip, r-release: signatureSurvival_1.0.0.zip, r-oldrel: signatureSurvival_1.0.0.zip |
macOS binaries: | r-release (arm64): signatureSurvival_1.0.0.tgz, r-oldrel (arm64): signatureSurvival_1.0.0.tgz, r-release (x86_64): signatureSurvival_1.0.0.tgz, r-oldrel (x86_64): signatureSurvival_1.0.0.tgz |
Please use the canonical form https://CRAN.R-project.org/package=signatureSurvival to link to this page.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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