paramlink2: Parametric Linkage Analysis

Parametric linkage analysis of monogenic traits in medical pedigrees. Features include singlepoint analysis, multipoint analysis via 'MERLIN' (Abecasis et al. (2002) <doi:10.1038/ng786>), visualisation of log of the odds (LOD) scores and summaries of linkage peaks. Disease models may be specified to accommodate phenocopies, reduced penetrance and liability classes. 'paramlink2' is part of the 'pedsuite' package ecosystem, presented in 'Pedigree Analysis in R' (Vigeland, 2021, ISBN:9780128244302).

Version:	1.0.6
Depends:	R (≥ 4.1), pedtools
Imports:	pedprobr
Suggests:	spelling, testthat
Published:	2024-09-07
DOI:	10.32614/CRAN.package.paramlink2
Author:	Magnus Dehli Vigeland [aut, cre]
Maintainer:	Magnus Dehli Vigeland <m.d.vigeland at medisin.uio.no>
BugReports:	https://github.com/magnusdv/paramlink2/issues
License:	GPL-3
URL:	https://github.com/magnusdv/paramlink2
NeedsCompilation:	no
SystemRequirements:	MERLIN (https://csg.sph.umich.edu/abecasis/merlin/) for multipoint linkage analysis.
Language:	en-GB
Materials:	README NEWS
CRAN checks:	paramlink2 results

Documentation:

Reference manual:

paramlink2.pdf

Downloads:

Package source:	paramlink2_1.0.6.tar.gz
Windows binaries:	r-devel: paramlink2_1.0.6.zip, r-release: paramlink2_1.0.6.zip, r-oldrel: paramlink2_1.0.6.zip
macOS binaries:	r-release (arm64): paramlink2_1.0.6.tgz, r-oldrel (arm64): paramlink2_1.0.6.tgz, r-release (x86_64): paramlink2_1.0.6.tgz, r-oldrel (x86_64): paramlink2_1.0.6.tgz
Old sources:	paramlink2 archive

Reverse dependencies:

Reverse imports:

pedsuite

Linking:

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