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joint.Cox: Joint Frailty-Copula Models for Tumour Progression and Death in Meta-Analysis

Fit survival data and perform dynamic prediction under joint frailty-copula models for tumour progression and death. Likelihood-based methods are employed for estimating model parameters, where the baseline hazard functions are modeled by the cubic M-spline or the Weibull model. The methods are applicable for meta-analytic data containing individual-patient information from several studies. Survival outcomes need information on both terminal event time (e.g., time-to-death) and non-terminal event time (e.g., time-to-tumour progression). Methodologies were published in Emura et al. (2017) <doi:10.1177/0962280215604510>, Emura et al. (2018) <doi:10.1177/0962280216688032>, Emura et al. (2020) <doi:10.1177/0962280219892295>, Shinohara et al. (2020) <doi:10.1080/03610918.2020.1855449>, Wu et al. (2020) <doi:10.1007/s00180-020-00977-1>, and Emura et al. (2021) <doi:10.1177/09622802211046390>. See also the book of Emura et al. (2019) <doi:10.1007/978-981-13-3516-7>. Survival data from ovarian cancer patients are also available.

Version: 3.16
Depends: survival
Published: 2022-02-04
Author: Takeshi Emura
Maintainer: Takeshi Emura <takeshiemura at gmail.com>
License: GPL-2
NeedsCompilation: no
In views: MetaAnalysis, Survival
CRAN checks: joint.Cox results

Documentation:

Reference manual: joint.Cox.pdf

Downloads:

Package source: joint.Cox_3.16.tar.gz
Windows binaries: r-devel: joint.Cox_3.16.zip, r-release: joint.Cox_3.16.zip, r-oldrel: joint.Cox_3.16.zip
macOS binaries: r-release (arm64): joint.Cox_3.16.tgz, r-oldrel (arm64): joint.Cox_3.16.tgz, r-release (x86_64): joint.Cox_3.16.tgz, r-oldrel (x86_64): joint.Cox_3.16.tgz
Old sources: joint.Cox archive

Reverse dependencies:

Reverse depends: GFGM.copula

Linking:

Please use the canonical form https://CRAN.R-project.org/package=joint.Cox to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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