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A minimal set of routines to calculate the Grantham distance <doi:10.1126/science.185.4154.862>. The Grantham distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.
Version: | 0.1.2 |
Depends: | R (≥ 2.10) |
Imports: | tibble, vctrs, dplyr |
Suggests: | spelling, testthat (≥ 3.0.0) |
Published: | 2024-07-30 |
DOI: | 10.32614/CRAN.package.grantham |
Author: | Ramiro Magno [aut, cre], Isabel Duarte [aut], Ana-Teresa Maia [aut], University of Algarve [fnd], CINTESIS [fnd], Pattern Institute [cph, fnd] |
Maintainer: | Ramiro Magno <rmagno at pattern.institute> |
BugReports: | https://github.com/patterninstitute/grantham/issues |
License: | MIT + file LICENSE |
URL: | https://www.pattern.institute/grantham/, https://github.com/patterninstitute/grantham |
NeedsCompilation: | no |
Language: | en-US |
Materials: | README NEWS |
CRAN checks: | grantham results |
Reference manual: | grantham.pdf |
Package source: | grantham_0.1.2.tar.gz |
Windows binaries: | r-devel: grantham_0.1.2.zip, r-release: grantham_0.1.2.zip, r-oldrel: grantham_0.1.2.zip |
macOS binaries: | r-release (arm64): grantham_0.1.2.tgz, r-oldrel (arm64): grantham_0.1.2.tgz, r-release (x86_64): grantham_0.1.2.tgz, r-oldrel (x86_64): grantham_0.1.2.tgz |
Old sources: | grantham archive |
Reverse imports: | agvgd |
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