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grantham: Calculate the 'Grantham' Distance
A minimal set of routines to calculate the 'Grantham' distance
<doi:10.1126/science.185.4154.862>. The 'Grantham' distance attempts to
provide a proxy for the evolutionary distance between two amino acids
based on three key chemical properties: composition, polarity and
molecular volume. In turn, evolutionary distance is used as a proxy for
the impact of missense mutations. The higher the distance, the more
deleterious the substitution is expected to be.
| Version: |
0.1.1 |
| Depends: |
R (≥ 2.10) |
| Imports: |
tibble, magrittr, vctrs, dplyr, tidyr, rlang, stringr |
| Suggests: |
spelling |
| Published: |
2022-01-07 |
| Author: |
Ramiro Magno 
[aut, cre],
Isabel Duarte
[aut],
Ana-Teresa Maia
[aut],
CINTESIS [cph, fnd] |
| Maintainer: |
Ramiro Magno <ramiro.magno at gmail.com> |
| BugReports: |
https://github.com/maialab/grantham/issues |
| License: |
MIT + file LICENSE |
| URL: |
https://maialab.org/grantham/, https://github.com/maialab/grantham |
| NeedsCompilation: |
no |
| Language: |
en-US |
| Materials: |
README NEWS |
| CRAN checks: |
grantham results |
Documentation:
Downloads:
Reverse dependencies:
Linking:
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https://CRAN.R-project.org/package=grantham
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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