famSKATRC: Family Sequence Kernel Association Test for Rare and Common Variants

FamSKAT-RC is a family-based association kernel test for both rare and common variants. This test is general and several special cases are known as other methods: famSKAT, which only focuses on rare variants in family-based data, SKAT, which focuses on rare variants in population-based data (unrelated individuals), and SKAT-RC, which focuses on both rare and common variants in population-based data. When one applies famSKAT-RC and sets the value of phi to 1, famSKAT-RC becomes famSKAT. When one applies famSKAT-RC and set the value of phi to 1 and the kinship matrix to the identity matrix, famSKAT-RC becomes SKAT. When one applies famSKAT-RC and set the kinship matrix (fullkins) to the identity matrix (and phi is not equal to 1), famSKAT-RC becomes SKAT-RC. We also include a small sample synthetic pedigree to demonstrate the method with. For more details see Saad M and Wijsman EM (2014) <doi:10.1002/gepi.21844>.

Version:	1.1.0
Depends:	R (≥ 3.4.1)
Imports:	CompQuadForm, kinship2, coxme, bdsmatrix
Published:	2017-11-09
DOI:	10.32614/CRAN.package.famSKATRC
Author:	Khalid B. Kunji [aut, cre], Mohamad Saad [aut]
Maintainer:	Khalid B. Kunji <kkunji at hbku.edu.qa>
License:	GPL (≥ 3)
URL:	https://www.r-project.org, https://www.ncbi.nlm.nih.gov/pubmed/25132070
NeedsCompilation:	no
CRAN checks:	famSKATRC results

Documentation:

Reference manual:

famSKATRC.pdf

Downloads:

Package source:	famSKATRC_1.1.0.tar.gz
Windows binaries:	r-devel: famSKATRC_1.1.0.zip, r-release: famSKATRC_1.1.0.zip, r-oldrel: famSKATRC_1.1.0.zip
macOS binaries:	r-release (arm64): famSKATRC_1.1.0.tgz, r-oldrel (arm64): famSKATRC_1.1.0.tgz, r-release (x86_64): famSKATRC_1.1.0.tgz, r-oldrel (x86_64): famSKATRC_1.1.0.tgz
Old sources:	famSKATRC archive

Reverse dependencies:

Reverse imports:

Mega2R

Linking:

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