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famSKATRC: Family Sequence Kernel Association Test for Rare and Common Variants

FamSKAT-RC is a family-based association kernel test for both rare and common variants. This test is general and several special cases are known as other methods: famSKAT, which only focuses on rare variants in family-based data, SKAT, which focuses on rare variants in population-based data (unrelated individuals), and SKAT-RC, which focuses on both rare and common variants in population-based data. When one applies famSKAT-RC and sets the value of phi to 1, famSKAT-RC becomes famSKAT. When one applies famSKAT-RC and set the value of phi to 1 and the kinship matrix to the identity matrix, famSKAT-RC becomes SKAT. When one applies famSKAT-RC and set the kinship matrix (fullkins) to the identity matrix (and phi is not equal to 1), famSKAT-RC becomes SKAT-RC. We also include a small sample synthetic pedigree to demonstrate the method with. For more details see Saad M and Wijsman EM (2014) <doi:10.1002/gepi.21844>.

Version: 1.1.0
Depends: R (≥ 3.4.1)
Imports: CompQuadForm, kinship2, coxme, bdsmatrix
Published: 2017-11-09
DOI: 10.32614/CRAN.package.famSKATRC
Author: Khalid B. Kunji [aut, cre], Mohamad Saad [aut]
Maintainer: Khalid B. Kunji <kkunji at hbku.edu.qa>
License: GPL (≥ 3)
URL: https://www.r-project.org, https://www.ncbi.nlm.nih.gov/pubmed/25132070
NeedsCompilation: no
CRAN checks: famSKATRC results

Documentation:

Reference manual: famSKATRC.pdf

Downloads:

Package source: famSKATRC_1.1.0.tar.gz
Windows binaries: r-devel: famSKATRC_1.1.0.zip, r-release: famSKATRC_1.1.0.zip, r-oldrel: famSKATRC_1.1.0.zip
macOS binaries: r-release (arm64): famSKATRC_1.1.0.tgz, r-oldrel (arm64): famSKATRC_1.1.0.tgz, r-release (x86_64): famSKATRC_1.1.0.tgz, r-oldrel (x86_64): famSKATRC_1.1.0.tgz
Old sources: famSKATRC archive

Reverse dependencies:

Reverse imports: Mega2R

Linking:

Please use the canonical form https://CRAN.R-project.org/package=famSKATRC to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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