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Colocalisation analysis tests whether two traits share a causal genetic variant in a specified genomic region. Proportional testing for colocalisation has been previously proposed [Wallace (2013) <doi:10.1002/gepi.21765>], but is reimplemented here to overcome barriers to its adoption. Its use is complementary to the fine- mapping based colocalisation method in the 'coloc' package, and may be used in particular to identify false "H3" conclusions in 'coloc'.
Version: | 0.9.1 |
Depends: | magrittr, data.table |
Imports: | car, coloc, graphics, stats, utils |
Suggests: | knitr, plotrix, testthat (≥ 3.0.0) |
Published: | 2024-06-11 |
DOI: | 10.32614/CRAN.package.colocPropTest |
Author: | Chris Wallace |
Maintainer: | Chris Wallace <chris.x.wallace at gsk.com> |
License: | GPL (≥ 3) |
NeedsCompilation: | no |
Materials: | README |
CRAN checks: | colocPropTest results |
Reference manual: | colocPropTest.pdf |
Vignettes: |
Proportional colocalisation |
Package source: | colocPropTest_0.9.1.tar.gz |
Windows binaries: | r-devel: colocPropTest_0.9.1.zip, r-release: colocPropTest_0.9.1.zip, r-oldrel: colocPropTest_0.9.1.zip |
macOS binaries: | r-release (arm64): colocPropTest_0.9.1.tgz, r-oldrel (arm64): colocPropTest_0.9.1.tgz, r-release (x86_64): colocPropTest_0.9.1.tgz, r-oldrel (x86_64): colocPropTest_0.9.1.tgz |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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