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Bayesian and ML Emax model fitting, graphics and simulation for clinical dose response. The summary data from the dose response meta-analyses in Thomas, Sweeney, and Somayaji (2014) <doi:10.1080/19466315.2014.924876> and Thomas and Roy (2016) <doi:10.1080/19466315.2016.1256229> Wu, Banerjee, Jin, Menon, Martin, and Heatherington(2017) <doi:10.1177/0962280216684528> are included in the package. The prior distributions for the Bayesian analyses default to the posterior predictive distributions derived from these references.
Version: | 2.4.1 |
Depends: | R (≥ 3.5.0), rstan (≥ 2.17.3), shiny |
Imports: | foreach, graphics, DoseFinding, stats, mvtnorm, utils, parallel, doParallel, ggplot2, tidyr, purrr, tibble, dplyr, glue, waiter |
Published: | 2023-08-09 |
DOI: | 10.32614/CRAN.package.clinDR |
Author: | Neal Thomas [aut, cre], Jing Wu [aut], Mike K. Smith [aut] |
Maintainer: | Neal Thomas <snthomas99 at gmail.com> |
License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
NeedsCompilation: | no |
Materials: | NEWS |
In views: | Pharmacokinetics |
CRAN checks: | clinDR results |
Reference manual: | clinDR.pdf |
Package source: | clinDR_2.4.1.tar.gz |
Windows binaries: | r-devel: clinDR_2.4.1.zip, r-release: clinDR_2.4.1.zip, r-oldrel: clinDR_2.4.1.zip |
macOS binaries: | r-release (arm64): clinDR_2.4.1.tgz, r-oldrel (arm64): clinDR_2.4.1.tgz, r-release (x86_64): clinDR_2.4.1.tgz, r-oldrel (x86_64): clinDR_2.4.1.tgz |
Old sources: | clinDR archive |
Reverse suggests: | BayesianMCPMod |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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