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caradpt: Covariate-Adjusted Response-Adaptive Designs for Clinical Trials

Tools for implementing covariate-adjusted response-adaptive procedures for binary, continuous and survival responses. Users can flexibly choose between two functions based on their specific needs for each procedure: use real patient data from clinical trials to compute allocation probabilities directly, or use built-in simulation functions to generate synthetic patient data. Detailed methodologies and algorithms used in this package are described in the following references: Zhang, L. X., Hu, F., Cheung, S. H., & Chan, W. S. (2007)<doi:10.1214/009053606000001424> Zhang, L. X. & Hu, F. (2009) <doi:10.1007/s11766-009-0001-6> Hu, J., Zhu, H., & Hu, F. (2015) <doi:10.1080/01621459.2014.903846> Zhao, W., Ma, W., Wang, F., & Hu, F. (2022) <doi:10.1002/pst.2160> Mukherjee, A., Jana, S., & Coad, S. (2024) <doi:10.1177/09622802241287704>.

Version: 0.1.0
Depends: R (≥ 3.6.0)
Imports: survival
Published: 2025-08-28
DOI: 10.32614/CRAN.package.caradpt
Author: Renjie Luo [aut, cre], Feifang Hu [aut, ctb]
Maintainer: Renjie Luo <jerry.luorj at gmail.com>
License: GPL-3
NeedsCompilation: no
CRAN checks: caradpt results

Documentation:

Reference manual: caradpt.html , caradpt.pdf

Downloads:

Package source: caradpt_0.1.0.tar.gz
Windows binaries: r-devel: caradpt_0.1.0.zip, r-release: not available, r-oldrel: caradpt_0.1.0.zip
macOS binaries: r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): caradpt_0.1.0.tgz, r-oldrel (x86_64): caradpt_0.1.0.tgz

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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