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adaptIVPT: Adaptive Bioequivalence Design for In-Vitro Permeation Tests

Contains functions carrying out adaptive procedures using mixed scaling approach to establish bioequivalence for in-vitro permeation test (IVPT) data. Currently, the package provides procedures based on parallel replicate design and balanced data, according to the U.S. Food and Drug Administration's "Draft Guidance on Acyclovir" <https://www.accessdata.fda.gov/drugsatfda_docs/psg/Acyclovir_topical%20cream_RLD%2021478_RV12-16.pdf>. Potvin et al. (2008) <doi:10.1002/pst.294> provides the basis for our adaptive design (see Method B). For a comprehensive overview of the method, refer to Lim et al. (2023) <doi:10.1002/pst.2333>. This package reflects the views of the authors and should not be construed to represent the views or policies of the U.S. Food and Drug Administration.

Version: 1.1.0
Depends: R (≥ 3.4)
Imports: Rcpp, rgl
LinkingTo: Rcpp, RcppArmadillo, RcppProgress
Suggests: knitr, rmarkdown
Published: 2024-01-26
DOI: 10.32614/CRAN.package.adaptIVPT
Author: Daeyoung Lim [aut, cre], Elena Rantou [ctb], Jessica Kim [ctb], Sungwoo Choi [ctb], Nam Hee Choi [ctb], Stella Grosser [ctb]
Maintainer: Daeyoung Lim <Daeyoung.Lim at fda.hhs.gov>
License: GPL (≥ 3)
NeedsCompilation: yes
Citation: adaptIVPT citation info
Materials: NEWS
CRAN checks: adaptIVPT results

Documentation:

Reference manual: adaptIVPT.pdf

Downloads:

Package source: adaptIVPT_1.1.0.tar.gz
Windows binaries: r-devel: adaptIVPT_1.1.0.zip, r-release: adaptIVPT_1.1.0.zip, r-oldrel: adaptIVPT_1.1.0.zip
macOS binaries: r-release (arm64): adaptIVPT_1.1.0.tgz, r-oldrel (arm64): adaptIVPT_1.1.0.tgz, r-release (x86_64): adaptIVPT_1.1.0.tgz, r-oldrel (x86_64): adaptIVPT_1.1.0.tgz
Old sources: adaptIVPT archive

Linking:

Please use the canonical form https://CRAN.R-project.org/package=adaptIVPT to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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