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A system to simulate clinical trials with time to event endpoints. Event simulation is based on Cox models allowing for covariates in addition to the treatment or group factor. Specific drop-out rates (separate from administrative censoring) can be controlled in the simulation. Other features include stratified randomization, non-proportional hazards, different accrual patterns, and event projection (timing to reach the target event) based on interim data.
| Version: | 0.2 |
| Depends: | R (≥ 4.0.0), blockrand, dplyr, survival, simsurv |
| Published: | 2021-02-26 |
| DOI: | 10.32614/CRAN.package.TwoArmSurvSim |
| Author: | Bo Zhang [cre, aut], Yi Zhong [aut, ctb], Ginny Peng [aut, ctb], Bin Yao [aut, ctb] |
| Maintainer: | Bo Zhang <bzhang at pumabiotechnology.com> |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | no |
| CRAN checks: | TwoArmSurvSim results |
| Reference manual: | TwoArmSurvSim.pdf |
| Package source: | TwoArmSurvSim_0.2.tar.gz |
| Windows binaries: | r-devel: TwoArmSurvSim_0.2.zip, r-release: TwoArmSurvSim_0.2.zip, r-oldrel: TwoArmSurvSim_0.2.zip |
| macOS binaries: | r-release (arm64): TwoArmSurvSim_0.2.tgz, r-oldrel (arm64): TwoArmSurvSim_0.2.tgz, r-release (x86_64): TwoArmSurvSim_0.2.tgz, r-oldrel (x86_64): TwoArmSurvSim_0.2.tgz |
| Old sources: | TwoArmSurvSim archive |
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