The hardware and bandwidth for this mirror is donated by dogado GmbH, the Webhosting and Full Service-Cloud Provider. Check out our Wordpress Tutorial.
If you wish to report a bug, or if you are interested in having us mirror your free-software or open-source project, please feel free to contact us at mirror[@]dogado.de.
This tool is extended from methods in Bio.SeqUtils.MeltingTemp of python. The melting temperature of nucleic acid sequences can be calculated in three method, the Wallace rule (Thein & Wallace (1986) <doi:10.1016/S0140-6736(86)90739-7>), empirical formulas based on G and C content (Marmur J. (1962) <doi:10.1016/S0022-2836(62)80066-7>, Schildkraut C. (2010) <doi:10.1002/bip.360030207>, Wetmur J G (1991) <doi:10.3109/10409239109114069>, Untergasser,A. (2012) <doi:10.1093/nar/gks596>, von Ahsen N (2001) <doi:10.1093/clinchem/47.11.1956>) and nearest neighbor thermodynamics (Breslauer K J (1986) <doi:10.1073/pnas.83.11.3746>, Sugimoto N (1996) <doi:10.1093/nar/24.22.4501>, Allawi H (1998) <doi:10.1093/nar/26.11.2694>, SantaLucia J (2004) <doi:10.1146/annurev.biophys.32.110601.141800>, Freier S (1986) <doi:10.1073/pnas.83.24.9373>, Xia T (1998) <doi:10.1021/bi9809425>, Chen JL (2012) <doi:10.1021/bi3002709>, Bommarito S (2000) <doi:10.1093/nar/28.9.1929>, Turner D H (2010) <doi:10.1093/nar/gkp892>, Sugimoto N (1995) <doi:10.1016/S0048-9697(98)00088-6>, Allawi H T (1997) <doi:10.1021/bi962590c>, Santalucia N (2005) <doi:10.1093/nar/gki918>), and it can also be corrected with salt ions and chemical compound (SantaLucia J (1996) <doi:10.1021/bi951907q>, SantaLucia J(1998) <doi:10.1073/pnas.95.4.1460>, Owczarzy R (2004) <doi:10.1021/bi034621r>, Owczarzy R (2008) <doi:10.1021/bi702363u>).
| Version: | 1.0.3 |
| Depends: | R (≥ 2.10) |
| Published: | 2022-02-21 |
| DOI: | 10.32614/CRAN.package.TmCalculator |
| Author: | Junhui Li |
| Maintainer: | Junhui Li <junhuili at cau.edu.cn> |
| BugReports: | https://github.com/JunhuiLi1017/TmCalculator/issues |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | no |
| CRAN checks: | TmCalculator results |
| Reference manual: | TmCalculator.pdf |
| Package source: | TmCalculator_1.0.3.tar.gz |
| Windows binaries: | r-devel: TmCalculator_1.0.3.zip, r-release: TmCalculator_1.0.3.zip, r-oldrel: TmCalculator_1.0.3.zip |
| macOS binaries: | r-release (arm64): TmCalculator_1.0.3.tgz, r-oldrel (arm64): TmCalculator_1.0.3.tgz, r-release (x86_64): TmCalculator_1.0.3.tgz, r-oldrel (x86_64): TmCalculator_1.0.3.tgz |
| Old sources: | TmCalculator archive |
| Reverse imports: | ProbeDeveloper |
| Reverse suggests: | disprose |
Please use the canonical form https://CRAN.R-project.org/package=TmCalculator to link to this page.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
Health stats visible at Monitor.