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We provide a comprehensive scheme that is capable of simulating Single Cell RNA Sequencing data for various parameters of Biological Coefficient of Variation, busting kinetics, differential expression (DE), cell or sample groups, cell trajectory, batch effect and other experimental designs. 'SCRIP' proposed and compared two frameworks with Gamma-Poisson and Beta-Gamma-Poisson models for simulating Single Cell RNA Sequencing data. Other reference is available in Zappia et al. (2017) <https://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1305-0>.
Version: | 1.0.0 |
Depends: | R (≥ 4.0) |
Imports: | splatter (≥ 1.16.1), S4Vectors (≥ 0.30.0), SummarizedExperiment (≥ 1.22.0), SingleCellExperiment (≥ 1.14.1), edgeR (≥ 3.34.0), methods, stats, mgcv, knitr, BiocManager, BiocGenerics, Seurat, crayon, fitdistrplus, checkmate (≥ 2.0.0) |
Suggests: | rmarkdown, testthat (≥ 3.0.0) |
Published: | 2021-11-19 |
DOI: | 10.32614/CRAN.package.SCRIP |
Author: | Fei Qin [aut, cre, cph] |
Maintainer: | Fei Qin <fqin at email.sc.edu> |
License: | GPL-3 |
URL: | https://github.com/thecailab/SCRIP |
NeedsCompilation: | no |
Language: | en-GB |
CRAN checks: | SCRIP results |
Reference manual: | SCRIP.pdf |
Vignettes: |
SCRIPsimu |
Package source: | SCRIP_1.0.0.tar.gz |
Windows binaries: | r-devel: SCRIP_1.0.0.zip, r-release: SCRIP_1.0.0.zip, r-oldrel: SCRIP_1.0.0.zip |
macOS binaries: | r-release (arm64): SCRIP_1.0.0.tgz, r-oldrel (arm64): SCRIP_1.0.0.tgz, r-release (x86_64): SCRIP_1.0.0.tgz, r-oldrel (x86_64): SCRIP_1.0.0.tgz |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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