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Construct pharmacogenomics (PGx) polygenic risk score (PRS) with PRS-PGx-Unadj (unadjusted), PRS-PGx-CT (clumping and thresholding), PRS-PGx-L, -GL, -SGL (penalized regression), PRS-PGx-Bayes (Bayesian regression). Package is based on ”Pharmacogenomics Polyenic Risk Score for Drug Response Prediction Using PRS-PGx Methods” by Zhai, S., Zhang, H., Mehrotra, D.V., and Shen, J., 2021 (submitted).
Version: | 0.3.0 |
Depends: | R (≥ 4.0.0) |
Imports: | gglasso (≥ 1.5.0), SGL (≥ 1.3.0), glmnet (≥ 4.0.2), bigsnpr (≥ 1.5.2), Matrix (≥ 1.2.18), GIGrvg (≥ 0.5.0), MCMCpack (≥ 1.4.6), bdsmatrix (≥ 1.3.4), bigsparser (≥ 0.4.0), lmtest (≥ 0.9.37), mvtnorm (≥ 1.1.0), propagate (≥ 1.0.6), bigparallelr (≥ 0.2.3), methods (≥ 3.6.3), bigstatsr (≥ 1.2.3), Rfast (≥ 1.9.9), matrixcalc (≥ 1.0-3) |
Suggests: | knitr, rmarkdown |
Published: | 2022-07-20 |
DOI: | 10.32614/CRAN.package.PRSPGx |
Author: | Song Zhai [aut, cre] |
Maintainer: | Song Zhai <zsviolet1993 at gmail.com> |
License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
NeedsCompilation: | yes |
CRAN checks: | PRSPGx results |
Reference manual: | PRSPGx.pdf |
Vignettes: |
Put the title of your vignette here |
Package source: | PRSPGx_0.3.0.tar.gz |
Windows binaries: | r-devel: PRSPGx_0.3.0.zip, r-release: PRSPGx_0.3.0.zip, r-oldrel: PRSPGx_0.3.0.zip |
macOS binaries: | r-release (arm64): PRSPGx_0.3.0.tgz, r-oldrel (arm64): PRSPGx_0.3.0.tgz, r-release (x86_64): PRSPGx_0.3.0.tgz, r-oldrel (x86_64): PRSPGx_0.3.0.tgz |
Old sources: | PRSPGx archive |
Please use the canonical form https://CRAN.R-project.org/package=PRSPGx to link to this page.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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