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Conduct simulation-based customized power calculation for clustered time to event data in a mixed crossed/nested design, where a number of cell lines and a number of mice within each cell line are considered to achieve a desired statistical power, motivated by Eckel-Passow and colleagues (2021) <doi:10.1093/neuonc/noab137> and Li and colleagues (2024) <doi:10.48550/arXiv.2404.08927>. This package provides two commonly used models for powering a design, linear mixed effects and Cox frailty model. Both models account for within-subject (cell line) correlation while holding different distributional assumptions about the outcome. Alternatively, the counterparts of fixed effects model are also available, which produces similar estimates of statistical power.
| Version: | 1.0.3 |
| Depends: | R (≥ 3.5.0), survival, stats, parallel |
| Imports: | nlme, ggplot2, ggpubr, frailtypack |
| Suggests: | testthat (≥ 3.0.0), spelling |
| Published: | 2024-07-31 |
| DOI: | 10.32614/CRAN.package.PDXpower |
| Author: | Shanpeng Li [aut, cre], Gang Li [ctb] |
| Maintainer: | Shanpeng Li <lishanpeng0913 at ucla.edu> |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | no |
| Language: | en-US |
| Materials: | README |
| CRAN checks: | PDXpower results |
| Reference manual: | PDXpower.pdf |
| Package source: | PDXpower_1.0.3.tar.gz |
| Windows binaries: | r-devel: PDXpower_1.0.3.zip, r-release: PDXpower_1.0.3.zip, r-oldrel: PDXpower_1.0.3.zip |
| macOS binaries: | r-release (arm64): PDXpower_1.0.3.tgz, r-oldrel (arm64): PDXpower_1.0.3.tgz, r-release (x86_64): PDXpower_1.0.3.tgz, r-oldrel (x86_64): PDXpower_1.0.3.tgz |
| Old sources: | PDXpower archive |
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