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A genetic analysis tool and variance component model for identifying marginal epistasis between pathways and the rest of the genome. 'MAPITR' uses as input a matrix of genotypes, a vector of phenotypes, and a list of pathways. 'MAPITR' then iteratively tests each pathway for epistasis between any variants within the pathway versus any variants remaining in the rest of the genome. 'MAPITR' returns results in the form of p-values for every pathway indicating whether the null model of there being no epistatic interactions between a pathway and the rest of the genome can be rejected.
Version: | 1.1.2 |
Depends: | R (≥ 3.3.0) |
Imports: | stats, doParallel, Rcpp (≥ 1.0.5), CompQuadForm |
LinkingTo: | Rcpp, RcppArmadillo |
Suggests: | testthat, knitr, rmarkdown |
Published: | 2020-09-28 |
DOI: | 10.32614/CRAN.package.MAPITR |
Author: | Michael Turchin |
Maintainer: | Michael Turchin <michael_turchin at brown.edu> |
BugReports: | https://github.com/mturchin20/MAPITR/issues |
License: | MIT + file LICENSE |
URL: | https://github.com/mturchin20/MAPITR |
NeedsCompilation: | yes |
Materials: | README |
CRAN checks: | MAPITR results |
Reference manual: | MAPITR.pdf |
Vignettes: |
MAPITR Introduction – Simulated Data |
Package source: | MAPITR_1.1.2.tar.gz |
Windows binaries: | r-devel: MAPITR_1.1.2.zip, r-release: MAPITR_1.1.2.zip, r-oldrel: MAPITR_1.1.2.zip |
macOS binaries: | r-release (arm64): MAPITR_1.1.2.tgz, r-oldrel (arm64): MAPITR_1.1.2.tgz, r-release (x86_64): MAPITR_1.1.2.tgz, r-oldrel (x86_64): MAPITR_1.1.2.tgz |
Old sources: | MAPITR archive |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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