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A computationally efficient and statistically rigorous fast Kernel Machine method for multi-kernel analysis. The approach is based on a low-rank approximation to the nuisance effect kernel matrices. The algorithm is applicable to continuous, binary, and survival traits and is implemented using the existing single-kernel analysis software 'SKAT' and 'coxKM'. 'coxKM' can be obtained from <https://github.com/lin-lab/coxKM>.
Version: | 1.1 |
Depends: | rARPACK, stats, methods |
Suggests: | coxKM, SKAT, survival |
Published: | 2022-06-07 |
DOI: | 10.32614/CRAN.package.FastKM |
Author: | Rachel Marceau, Wenbin Lu, Michele M. Sale, Bradford B. Worrall, Stephen R. Williams, Fang-Chi Hsu, Jung-Ying Tzeng, and Shannon T. Holloway |
Maintainer: | Shannon T. Holloway <shannon.t.holloway at gmail.com> |
License: | GPL-2 |
NeedsCompilation: | no |
CRAN checks: | FastKM results |
Reference manual: | FastKM.pdf |
Package source: | FastKM_1.1.tar.gz |
Windows binaries: | r-devel: FastKM_1.1.zip, r-release: FastKM_1.1.zip, r-oldrel: FastKM_1.1.zip |
macOS binaries: | r-release (arm64): FastKM_1.1.tgz, r-oldrel (arm64): FastKM_1.1.tgz, r-release (x86_64): FastKM_1.1.tgz, r-oldrel (x86_64): FastKM_1.1.tgz |
Old sources: | FastKM archive |
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