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DTEAssurance: Assurance Methods for Clinical Trials with a Delayed Treatment Effect

Provides functions for planning clinical trials subject to a delayed treatment effect using assurance-based methods. Includes two 'shiny' applications for interactive exploration, simulation, and visualisation of trial designs and outcomes. The methodology is described in: Salsbury JA, Oakley JE, Julious SA, Hampson LV (2024) "Assurance methods for designing a clinical trial with a delayed treatment effect" <doi:10.1002/sim.10136>, Salsbury JA, Oakley JE, Julious SA, Hampson LV (2024) "Adaptive clinical trial design with delayed treatment effects using elicited prior distributions" <doi:10.48550/arXiv.2509.07602>.

Version: 1.0.0
Depends: R (≥ 4.0)
Imports: SHELF, shiny, stats, survival, nleqslv, nph, nphRCT, dplyr, rjags, rpact, magrittr, rlang, future.apply
Suggests: testthat (≥ 3.0.0)
Published: 2025-10-14
DOI: 10.32614/CRAN.package.DTEAssurance
Author: James Salsbury ORCID iD [aut, cre]
Maintainer: James Salsbury <jsalsbury1 at sheffield.ac.uk>
License: MIT + file LICENSE
URL: https://jamesalsbury.github.io/DTEAssurance/
NeedsCompilation: no
Materials: README, NEWS
CRAN checks: DTEAssurance results

Documentation:

Reference manual: DTEAssurance.html , DTEAssurance.pdf

Downloads:

Package source: DTEAssurance_1.0.0.tar.gz
Windows binaries: r-devel: DTEAssurance_1.0.0.zip, r-release: DTEAssurance_1.0.0.zip, r-oldrel: DTEAssurance_1.0.0.zip
macOS binaries: r-release (arm64): DTEAssurance_1.0.0.tgz, r-oldrel (arm64): DTEAssurance_1.0.0.tgz, r-release (x86_64): DTEAssurance_1.0.0.tgz, r-oldrel (x86_64): DTEAssurance_1.0.0.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=DTEAssurance to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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