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Prognostic Enrichment is a strategy of enriching a clinical trial for testing an intervention intended to prevent or delay an unwanted clinical event. A prognostically enriched trial enrolls only patients who are more likely to experience the unwanted clinical event than the broader patient population (R. Temple (2010) <doi:10.1038/clpt.2010.233>). By testing the intervention in an enriched study population, the trial may be adequately powered with a smaller sample size, which can have both practical and ethical advantages. This package provides tools to evaluate biomarkers for prognostic enrichment of clinical trials with survival/time-to-event outcomes.
| Version: | 0.1.0 |
| Depends: | R (≥ 3.1.0) |
| Imports: | survival, ggplot2, gridExtra |
| Published: | 2020-01-12 |
| DOI: | 10.32614/CRAN.package.BioPETsurv |
| Author: | Si Cheng [cre, aut], Kathleen F. Kerr [ctb] |
| Maintainer: | Si Cheng <chengsi at uw.edu> |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | no |
| CRAN checks: | BioPETsurv results |
| Reference manual: | BioPETsurv.pdf |
| Package source: | BioPETsurv_0.1.0.tar.gz |
| Windows binaries: | r-devel: BioPETsurv_0.1.0.zip, r-release: BioPETsurv_0.1.0.zip, r-oldrel: BioPETsurv_0.1.0.zip |
| macOS binaries: | r-release (arm64): BioPETsurv_0.1.0.tgz, r-oldrel (arm64): BioPETsurv_0.1.0.tgz, r-release (x86_64): BioPETsurv_0.1.0.tgz, r-oldrel (x86_64): BioPETsurv_0.1.0.tgz |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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