CRAN Package Check Results for Maintainer ‘Xiaowei Zhan <zhanxw at gmail.com>’

Last updated on 2025-12-04 07:52:02 CET.

Package ERROR WARN NOTE OK
cromwellDashboard 5 8
seqminer 9 2 1 1

Package cromwellDashboard

Current CRAN status: NOTE: 5, OK: 8

Version: 0.5.1
Check: CRAN incoming feasibility
Result: NOTE Maintainer: ‘Xiaowei Zhan <zhanxw@gmail.com>’ No Authors@R field in DESCRIPTION. Please add one, modifying Authors@R: person(given = "Xiaowei", family = "Zhan", role = c("aut", "cre"), email = "zhanxw@gmail.com") as necessary. Flavors: r-devel-linux-x86_64-debian-clang, r-devel-linux-x86_64-debian-gcc

Version: 0.5.1
Check: LazyData
Result: NOTE 'LazyData' is specified without a 'data' directory Flavors: r-oldrel-macos-arm64, r-oldrel-macos-x86_64, r-oldrel-windows-x86_64

Package seqminer

Current CRAN status: ERROR: 9, WARN: 2, NOTE: 1, OK: 1

Additional issues

rchk

Version: 9.7
Check: tests
Result: ERROR Running ‘testthat.R’ [3s/5s] Running the tests in ‘tests/testthat.R’ failed. Complete output: > ## follow http://adv-r.had.co.nz/Testing.html > print(sprintf("Test seqminer [version %s]", packageVersion("seqminer"))) [1] "Test seqminer [version 9.7]" > print("Platform") [1] "Platform" > print(str(.Platform)) List of 8 $ OS.type : chr "unix" $ file.sep : chr "/" $ dynlib.ext: chr ".so" $ GUI : chr "X11" $ endian : chr "little" $ pkgType : chr "source" $ path.sep : chr ":" $ r_arch : chr "" NULL > > print("Sys.info()") [1] "Sys.info()" > print(Sys.info()) sysname "Linux" release "6.12.22-amd64" version "#1 SMP PREEMPT_DYNAMIC Debian 6.12.22-1 (2025-04-10)" nodename "gimli2" machine "x86_64" login "hornik" user "hornik" effective_user "hornik" > > print(citation("seqminer")) To cite package 'seqminer' in publications use: Zhan X, Liu D (2015). "SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations." _Genetic Epidemiology_, *39*(8), 1242. doi:10.1002/gepi.21918 <https://doi.org/10.1002/gepi.21918>. seqminer version 9.7, <http://dx.doi.org/10.1002/gepi.21918>. A BibTeX entry for LaTeX users is @Article{, title = {SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations}, author = {Xiaowei Zhan and Dajiang J Liu}, journal = {Genetic Epidemiology}, volume = {39}, number = {8}, pages = {1242}, year = {2015}, note = {seqminer version 9.7}, web = {http:/zhanxw.github.io/seqminer}, publisher = {Wiley Online Library}, url = {http://dx.doi.org/10.1002/gepi.21918}, doi = {10.1002/gepi.21918}, } > > library(testthat) > library(seqminer) > ## ## test code are under inst/tests > ## ## test_package("seqminer", reporter="tap") > ## test_package("seqminer") > test_check("seqminer") 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/bi.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/bi.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:2" "1:3" [[1]] [1] "G" "G" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 Skipped: encounter a duplicated site: [ 1:1 ] in file [ /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/tri.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/tri.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:3" [[1]] [1] "T" "G" [[1]] [,1] [,2] [1,] 0.1993610 -0.0284801 [2,] -0.0284801 0.1139210 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1_A/G" "1:1_A/T" "1:3_A/G" [[1]] [1] "G" "T" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 [1] "=============" Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:1/1 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:1/1 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 [1] "=============" $pos [1] 1 2 3 $ref [1] "A" "A" "A" $alt [1] "G" "G" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" $pos [1] 1 1 3 $ref [1] "A" "A" "A" $alt [1] "G" "T" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" Skipped: encounter a duplicated site: [ 1:1 ] in file [ /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. Loading objects: apoe cfh cfh.all cfh.nonsyn cfh.nonsyn.2 cfh.range cfh.syn cfh.syn.2 out.gene.1 out.gene.2 out.gene.3 out.range.1 ssss --------------- test readVCFToMatrixByRange --------------- 1 region to be extracted. 1 region to be extracted. 2 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] 1 region to be extracted. range of [ APOE ] is [ 19:45409038-45412650 ] 1 region to be extracted. range of [ ssss ] is [ ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 1 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 start file = /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/plink/all.anno.filtered.extract Tue Dec 2 08:26:25 2025 - read bim Tue Dec 2 08:26:25 2025 - read fam extract 2 marker and 3 sample out of 166 marker and 3 sample Tue Dec 2 08:26:25 2025 - read bed Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim and dimnames Tue Dec 2 08:26:25 2025 - end --------------- test openPlink --------------- --------------- test readPlinkBySubscript --------------- start file = /home/hornik/tmp/R.check/r-devel-clang/Work/build/Packages/seqminer/plink/all.anno.filtered.extract.bed extract 2 marker and 3 sample out of 166 marker and 3 sample Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim Tue Dec 2 08:26:25 2025 - end --------------- test readSingleChromosomeVCFToMatrixByRange --------------- fsize = 2688 query [0, 0] Found 1 results found 1 position, e.g. 0 2384 Inferred 3 samples from header 1 region to be extracted. query [196621007, 196716634] Found 166 results found 166 position, e.g. 196623337 2454 --------------- test createSingleChromosomeVCFIndex --------------- header line has 3 samples offset = 2384 Indexing finished with 3 samples and 166 markers created index file [ /home/hornik/tmp/scratch/RtmptA8BRR/file902f3516879d7 ] Saving _problems/test-vcf-167.R --------------- test readSingleChromosomeBCFToMatrixByRange --------------- fsize = 2688 l_text = 4206 Total contig parse = 1, total header index used = 47 Inferred 3 samples from header 1 region to be extracted. query [196621006, 196716633] Found 166 results 196623336 4215 found 166 position, e.g. 196623336 4215 sampleNames.size() = 3, markerNames.size() = 166 --------------- test createSingleChromosomeBCFIndex --------------- l_text = 4206 Total contig parse = 1, total header index used = 47 offset_header = 4135 sample size = 3 last character is s[after_chrom_size-1] = 0 Indexing finished with 3 samples and 166 markers created index file [ /home/hornik/tmp/scratch/RtmptA8BRR/file902f356e030a3 ] Saving _problems/test-vcf-181.R [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] ══ Failed tests ════════════════════════════════════════════════════════════════ ── Error ('test-vcf.R:167:5'): createSingleChromosomeVCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:167:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) ── Error ('test-vcf.R:181:5'): createSingleChromosomeBCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:181:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] Error: ! Test failures. Execution halted Flavor: r-devel-linux-x86_64-debian-clang

Version: 9.7
Check: tests
Result: ERROR Running ‘testthat.R’ [2s/3s] Running the tests in ‘tests/testthat.R’ failed. Complete output: > ## follow http://adv-r.had.co.nz/Testing.html > print(sprintf("Test seqminer [version %s]", packageVersion("seqminer"))) [1] "Test seqminer [version 9.7]" > print("Platform") [1] "Platform" > print(str(.Platform)) List of 8 $ OS.type : chr "unix" $ file.sep : chr "/" $ dynlib.ext: chr ".so" $ GUI : chr "X11" $ endian : chr "little" $ pkgType : chr "source" $ path.sep : chr ":" $ r_arch : chr "" NULL > > print("Sys.info()") [1] "Sys.info()" > print(Sys.info()) sysname "Linux" release "6.12.22-amd64" version "#1 SMP PREEMPT_DYNAMIC Debian 6.12.22-1 (2025-04-10)" nodename "gimli1" machine "x86_64" login "hornik" user "hornik" effective_user "hornik" > > print(citation("seqminer")) To cite package 'seqminer' in publications use: Zhan X, Liu D (2015). "SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations." _Genetic Epidemiology_, *39*(8), 1242. doi:10.1002/gepi.21918 <https://doi.org/10.1002/gepi.21918>. seqminer version 9.7, <http://dx.doi.org/10.1002/gepi.21918>. A BibTeX entry for LaTeX users is @Article{, title = {SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations}, author = {Xiaowei Zhan and Dajiang J Liu}, journal = {Genetic Epidemiology}, volume = {39}, number = {8}, pages = {1242}, year = {2015}, note = {seqminer version 9.7}, web = {http:/zhanxw.github.io/seqminer}, publisher = {Wiley Online Library}, url = {http://dx.doi.org/10.1002/gepi.21918}, doi = {10.1002/gepi.21918}, } > > library(testthat) > library(seqminer) > ## ## test code are under inst/tests > ## ## test_package("seqminer", reporter="tap") > ## test_package("seqminer") > test_check("seqminer") 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/bi.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/bi.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:2" "1:3" [[1]] [1] "G" "G" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 Skipped: encounter a duplicated site: [ 1:1 ] in file [ /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:3" [[1]] [1] "T" "G" [[1]] [,1] [,2] [1,] 0.1993610 -0.0284801 [2,] -0.0284801 0.1139210 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1_A/G" "1:1_A/T" "1:3_A/G" [[1]] [1] "G" "T" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 [1] "=============" Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:1/1 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:1/1 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 [1] "=============" $pos [1] 1 2 3 $ref [1] "A" "A" "A" $alt [1] "G" "G" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" $pos [1] 1 1 3 $ref [1] "A" "A" "A" $alt [1] "G" "T" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" Skipped: encounter a duplicated site: [ 1:1 ] in file [ /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. Loading objects: apoe cfh cfh.all cfh.nonsyn cfh.nonsyn.2 cfh.range cfh.syn cfh.syn.2 out.gene.1 out.gene.2 out.gene.3 out.range.1 ssss --------------- test readVCFToMatrixByRange --------------- 1 region to be extracted. 1 region to be extracted. 2 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] 1 region to be extracted. range of [ APOE ] is [ 19:45409038-45412650 ] 1 region to be extracted. range of [ ssss ] is [ ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 1 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 start file = /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/plink/all.anno.filtered.extract Wed Dec 3 18:26:31 2025 - read bim Wed Dec 3 18:26:31 2025 - read fam extract 2 marker and 3 sample out of 166 marker and 3 sample Wed Dec 3 18:26:31 2025 - read bed Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim and dimnames Wed Dec 3 18:26:31 2025 - end --------------- test openPlink --------------- --------------- test readPlinkBySubscript --------------- start file = /home/hornik/tmp/R.check/r-devel-gcc/Work/build/Packages/seqminer/plink/all.anno.filtered.extract.bed extract 2 marker and 3 sample out of 166 marker and 3 sample Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim Wed Dec 3 18:26:31 2025 - end --------------- test readSingleChromosomeVCFToMatrixByRange --------------- fsize = 2688 query [0, 0] Found 1 results found 1 position, e.g. 0 2384 Inferred 3 samples from header 1 region to be extracted. query [196621007, 196716634] Found 166 results found 166 position, e.g. 196623337 2454 --------------- test createSingleChromosomeVCFIndex --------------- header line has 3 samples offset = 2384 Indexing finished with 3 samples and 166 markers created index file [ /tmp/RtmpufggVF/file2a39d7f11461f ] Saving _problems/test-vcf-167.R --------------- test readSingleChromosomeBCFToMatrixByRange --------------- fsize = 2688 l_text = 4206 Total contig parse = 1, total header index used = 47 Inferred 3 samples from header 1 region to be extracted. query [196621006, 196716633] Found 166 results 196623336 4215 found 166 position, e.g. 196623336 4215 sampleNames.size() = 3, markerNames.size() = 166 --------------- test createSingleChromosomeBCFIndex --------------- l_text = 4206 Total contig parse = 1, total header index used = 47 offset_header = 4135 sample size = 3 last character is s[after_chrom_size-1] = 0 Indexing finished with 3 samples and 166 markers created index file [ /tmp/RtmpufggVF/file2a39d51ea9519 ] Saving _problems/test-vcf-181.R [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] ══ Failed tests ════════════════════════════════════════════════════════════════ ── Error ('test-vcf.R:167:5'): createSingleChromosomeVCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:167:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) ── Error ('test-vcf.R:181:5'): createSingleChromosomeBCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:181:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] Error: ! Test failures. Execution halted Flavor: r-devel-linux-x86_64-debian-gcc

Version: 9.7
Check: tests
Result: ERROR Running ‘testthat.R’ Running the tests in ‘tests/testthat.R’ failed. Complete output: > ## follow http://adv-r.had.co.nz/Testing.html > print(sprintf("Test seqminer [version %s]", packageVersion("seqminer"))) [1] "Test seqminer [version 9.7]" > print("Platform") [1] "Platform" > print(str(.Platform)) List of 8 $ OS.type : chr "unix" $ file.sep : chr "/" $ dynlib.ext: chr ".so" $ GUI : chr "X11" $ endian : chr "little" $ pkgType : chr "source" $ path.sep : chr ":" $ r_arch : chr "" NULL > > print("Sys.info()") [1] "Sys.info()" > print(Sys.info()) sysname "Linux" release "6.14.6-300.fc42.x86_64" version "#1 SMP PREEMPT_DYNAMIC Fri May 9 20:11:19 UTC 2025" nodename "gannet.stats.ox.ac.uk" machine "x86_64" login "ripley" user "ripley" effective_user "ripley" > > print(citation("seqminer")) To cite package 'seqminer' in publications use: Zhan X, Liu D (2015). "SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations." _Genetic Epidemiology_, *39*(8), 1242. doi:10.1002/gepi.21918 <https://doi.org/10.1002/gepi.21918>. seqminer version 9.7, <http://dx.doi.org/10.1002/gepi.21918>. A BibTeX entry for LaTeX users is @Article{, title = {SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations}, author = {Xiaowei Zhan and Dajiang J Liu}, journal = {Genetic Epidemiology}, volume = {39}, number = {8}, pages = {1242}, year = {2015}, note = {seqminer version 9.7}, web = {http:/zhanxw.github.io/seqminer}, publisher = {Wiley Online Library}, url = {http://dx.doi.org/10.1002/gepi.21918}, doi = {10.1002/gepi.21918}, } > > library(testthat) > library(seqminer) > ## ## test code are under inst/tests > ## ## test_package("seqminer", reporter="tap") > ## test_package("seqminer") > test_check("seqminer") 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/bi.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/bi.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:2" "1:3" [[1]] [1] "G" "G" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 Skipped: encounter a duplicated site: [ 1:1 ] in file [ /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/tri.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/tri.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:3" [[1]] [1] "T" "G" [[1]] [,1] [,2] [1,] 0.1993610 -0.0284801 [2,] -0.0284801 0.1139210 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1_A/G" "1:1_A/T" "1:3_A/G" [[1]] [1] "G" "T" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 [1] "=============" Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:1/1 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:1/1 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 [1] "=============" $pos [1] 1 2 3 $ref [1] "A" "A" "A" $alt [1] "G" "G" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" $pos [1] 1 1 3 $ref [1] "A" "A" "A" $alt [1] "G" "T" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" Skipped: encounter a duplicated site: [ 1:1 ] in file [ /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. Loading objects: apoe cfh cfh.all cfh.nonsyn cfh.nonsyn.2 cfh.range cfh.syn cfh.syn.2 out.gene.1 out.gene.2 out.gene.3 out.range.1 ssss --------------- test readVCFToMatrixByRange --------------- 1 region to be extracted. 1 region to be extracted. 2 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] 1 region to be extracted. range of [ APOE ] is [ 19:45409038-45412650 ] 1 region to be extracted. range of [ ssss ] is [ ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 1 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 start file = /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/plink/all.anno.filtered.extract Mon Dec 1 13:46:33 2025 - read bim Mon Dec 1 13:46:33 2025 - read fam extract 2 marker and 3 sample out of 166 marker and 3 sample Mon Dec 1 13:46:33 2025 - read bed Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim and dimnames Mon Dec 1 13:46:33 2025 - end --------------- test openPlink --------------- --------------- test readPlinkBySubscript --------------- start file = /data/gannet/ripley/R/packages/tests-clang/seqminer.Rcheck/seqminer/plink/all.anno.filtered.extract.bed extract 2 marker and 3 sample out of 166 marker and 3 sample Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim Mon Dec 1 13:46:33 2025 - end --------------- test readSingleChromosomeVCFToMatrixByRange --------------- fsize = 2688 query [0, 0] Found 1 results found 1 position, e.g. 0 2384 Inferred 3 samples from header 1 region to be extracted. query [196621007, 196716634] Found 166 results found 166 position, e.g. 196623337 2454 --------------- test createSingleChromosomeVCFIndex --------------- header line has 3 samples offset = 2384 Indexing finished with 3 samples and 166 markers created index file [ /tmp/RtmpABpUty/working_dir/RtmpNsOcKs/file1de56e4eaa81a0 ] Saving _problems/test-vcf-167.R --------------- test readSingleChromosomeBCFToMatrixByRange --------------- fsize = 2688 l_text = 4206 Total contig parse = 1, total header index used = 47 Inferred 3 samples from header 1 region to be extracted. query [196621006, 196716633] Found 166 results 196623336 4215 found 166 position, e.g. 196623336 4215 sampleNames.size() = 3, markerNames.size() = 166 --------------- test createSingleChromosomeBCFIndex --------------- l_text = 4206 Total contig parse = 1, total header index used = 47 offset_header = 4135 sample size = 3 last character is s[after_chrom_size-1] = 0 Indexing finished with 3 samples and 166 markers created index file [ /tmp/RtmpABpUty/working_dir/RtmpNsOcKs/file1de56e60720b7f ] Saving _problems/test-vcf-181.R [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] ══ Failed tests ════════════════════════════════════════════════════════════════ ── Error ('test-vcf.R:167:5'): createSingleChromosomeVCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:167:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) ── Error ('test-vcf.R:181:5'): createSingleChromosomeBCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:181:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] Error: ! Test failures. Execution halted Flavor: r-devel-linux-x86_64-fedora-clang

Version: 9.7
Check: tests
Result: ERROR Running ‘testthat.R’ [4s/11s] Running the tests in ‘tests/testthat.R’ failed. Complete output: > ## follow http://adv-r.had.co.nz/Testing.html > print(sprintf("Test seqminer [version %s]", packageVersion("seqminer"))) [1] "Test seqminer [version 9.7]" > print("Platform") [1] "Platform" > print(str(.Platform)) List of 8 $ OS.type : chr "unix" $ file.sep : chr "/" $ dynlib.ext: chr ".so" $ GUI : chr "X11" $ endian : chr "little" $ pkgType : chr "source" $ path.sep : chr ":" $ r_arch : chr "" NULL > > print("Sys.info()") [1] "Sys.info()" > print(Sys.info()) sysname "Linux" release "6.14.6-300.fc42.x86_64" version "#1 SMP PREEMPT_DYNAMIC Fri May 9 20:11:19 UTC 2025" nodename "gannet.stats.ox.ac.uk" machine "x86_64" login "ripley" user "ripley" effective_user "ripley" > > print(citation("seqminer")) To cite package 'seqminer' in publications use: Zhan X, Liu D (2015). "SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations." _Genetic Epidemiology_, *39*(8), 1242. doi:10.1002/gepi.21918 <https://doi.org/10.1002/gepi.21918>. seqminer version 9.7, <http://dx.doi.org/10.1002/gepi.21918>. A BibTeX entry for LaTeX users is @Article{, title = {SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations}, author = {Xiaowei Zhan and Dajiang J Liu}, journal = {Genetic Epidemiology}, volume = {39}, number = {8}, pages = {1242}, year = {2015}, note = {seqminer version 9.7}, web = {http:/zhanxw.github.io/seqminer}, publisher = {Wiley Online Library}, url = {http://dx.doi.org/10.1002/gepi.21918}, doi = {10.1002/gepi.21918}, } > > library(testthat) > library(seqminer) > ## ## test code are under inst/tests > ## ## test_package("seqminer", reporter="tap") > ## test_package("seqminer") > test_check("seqminer") 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/bi.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/bi.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:2" "1:3" [[1]] [1] "G" "G" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 Skipped: encounter a duplicated site: [ 1:1 ] in file [ /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/tri.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/tri.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:3" [[1]] [1] "T" "G" [[1]] [,1] [,2] [1,] 0.1993610 -0.0284801 [2,] -0.0284801 0.1139210 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1_A/G" "1:1_A/T" "1:3_A/G" [[1]] [1] "G" "T" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 [1] "=============" Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:1/1 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:1/1 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 [1] "=============" $pos [1] 1 2 3 $ref [1] "A" "A" "A" $alt [1] "G" "G" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" $pos [1] 1 1 3 $ref [1] "A" "A" "A" $alt [1] "G" "T" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" Skipped: encounter a duplicated site: [ 1:1 ] in file [ /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. Loading objects: apoe cfh cfh.all cfh.nonsyn cfh.nonsyn.2 cfh.range cfh.syn cfh.syn.2 out.gene.1 out.gene.2 out.gene.3 out.range.1 ssss --------------- test readVCFToMatrixByRange --------------- 1 region to be extracted. 1 region to be extracted. 2 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] 1 region to be extracted. range of [ APOE ] is [ 19:45409038-45412650 ] 1 region to be extracted. range of [ ssss ] is [ ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 1 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 start file = /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/plink/all.anno.filtered.extract Mon Nov 24 05:57:01 2025 - read bim Mon Nov 24 05:57:01 2025 - read fam extract 2 marker and 3 sample out of 166 marker and 3 sample Mon Nov 24 05:57:01 2025 - read bed Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim and dimnames Mon Nov 24 05:57:01 2025 - end --------------- test openPlink --------------- --------------- test readPlinkBySubscript --------------- start file = /data/gannet/ripley/R/packages/tests-devel/seqminer.Rcheck/seqminer/plink/all.anno.filtered.extract.bed extract 2 marker and 3 sample out of 166 marker and 3 sample Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim Mon Nov 24 05:57:01 2025 - end --------------- test readSingleChromosomeVCFToMatrixByRange --------------- fsize = 2688 query [0, 0] Found 1 results found 1 position, e.g. 0 2384 Inferred 3 samples from header 1 region to be extracted. query [196621007, 196716634] Found 166 results found 166 position, e.g. 196623337 2454 --------------- test createSingleChromosomeVCFIndex --------------- header line has 3 samples offset = 2384 Indexing finished with 3 samples and 166 markers created index file [ /tmp/Rtmpp7Kq3g/working_dir/Rtmpubvw1o/file2c66db71fd87b0 ] Saving _problems/test-vcf-167.R --------------- test readSingleChromosomeBCFToMatrixByRange --------------- fsize = 2688 l_text = 4206 Total contig parse = 1, total header index used = 47 Inferred 3 samples from header 1 region to be extracted. query [196621006, 196716633] Found 166 results 196623336 4215 found 166 position, e.g. 196623336 4215 sampleNames.size() = 3, markerNames.size() = 166 --------------- test createSingleChromosomeBCFIndex --------------- l_text = 4206 Total contig parse = 1, total header index used = 47 offset_header = 4135 sample size = 3 last character is s[after_chrom_size-1] = 0 Indexing finished with 3 samples and 166 markers created index file [ /tmp/Rtmpp7Kq3g/working_dir/Rtmpubvw1o/file2c66db3c270a49 ] Saving _problems/test-vcf-181.R [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] ══ Failed tests ════════════════════════════════════════════════════════════════ ── Error ('test-vcf.R:167:5'): createSingleChromosomeVCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:167:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) ── Error ('test-vcf.R:181:5'): createSingleChromosomeBCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:181:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] Error: ! Test failures. Execution halted Flavor: r-devel-linux-x86_64-fedora-gcc

Version: 9.7
Check: tests
Result: ERROR Running 'testthat.R' [3s] Running the tests in 'tests/testthat.R' failed. Complete output: > ## follow http://adv-r.had.co.nz/Testing.html > print(sprintf("Test seqminer [version %s]", packageVersion("seqminer"))) [1] "Test seqminer [version 9.7]" > print("Platform") [1] "Platform" > print(str(.Platform)) List of 8 $ OS.type : chr "windows" $ file.sep : chr "/" $ dynlib.ext: chr ".dll" $ GUI : chr "RTerm" $ endian : chr "little" $ pkgType : chr "win.binary" $ path.sep : chr ";" $ r_arch : chr "x64" NULL > > print("Sys.info()") [1] "Sys.info()" > print(Sys.info()) sysname release version nodename machine "Windows" "Server x64" "build 20348" "CRANWIN3" "x86-64" login user effective_user udomain "CRAN" "CRAN" "CRAN" "CRANWIN3" > > print(citation("seqminer")) To cite package 'seqminer' in publications use: Zhan X, Liu D (2015). "SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations." _Genetic Epidemiology_, *39*(8), 1242. doi:10.1002/gepi.21918 <https://doi.org/10.1002/gepi.21918>. seqminer version 9.7, <http://dx.doi.org/10.1002/gepi.21918>. A BibTeX entry for LaTeX users is @Article{, title = {SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations}, author = {Xiaowei Zhan and Dajiang J Liu}, journal = {Genetic Epidemiology}, volume = {39}, number = {8}, pages = {1242}, year = {2015}, note = {seqminer version 9.7}, web = {http:/zhanxw.github.io/seqminer}, publisher = {Wiley Online Library}, url = {http://dx.doi.org/10.1002/gepi.21918}, doi = {10.1002/gepi.21918}, } > > library(testthat) > library(seqminer) > ## ## test code are under inst/tests > ## ## test_package("seqminer", reporter="tap") > ## test_package("seqminer") > test_check("seqminer") 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/bi.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/bi.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:2" "1:3" [[1]] [1] "G" "G" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 Skipped: encounter a duplicated site: [ 1:1 ] in file [ D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/tri.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/tri.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:3" [[1]] [1] "T" "G" [[1]] [,1] [,2] [1,] 0.1993610 -0.0284801 [2,] -0.0284801 0.1139210 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1_A/G" "1:1_A/T" "1:3_A/G" [[1]] [1] "G" "T" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 [1] "=============" Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:1/1 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:1/1 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 [1] "=============" $pos [1] 1 2 3 $ref [1] "A" "A" "A" $alt [1] "G" "G" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" $pos [1] 1 1 3 $ref [1] "A" "A" "A" $alt [1] "G" "T" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" Skipped: encounter a duplicated site: [ 1:1 ] in file [ D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: D:/RCompile/CRANpkg/lib/4.6/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. Loading objects: apoe cfh cfh.all cfh.nonsyn cfh.nonsyn.2 cfh.range cfh.syn cfh.syn.2 out.gene.1 out.gene.2 out.gene.3 out.range.1 ssss --------------- test readVCFToMatrixByRange --------------- 1 region to be extracted. 1 region to be extracted. 2 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] 1 region to be extracted. range of [ APOE ] is [ 19:45409038-45412650 ] 1 region to be extracted. range of [ ssss ] is [ ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 1 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 start file = D:/RCompile/CRANpkg/lib/4.6/seqminer/plink/all.anno.filtered.extract Tue Dec 2 14:49:32 2025 - read bim Tue Dec 2 14:49:32 2025 - read fam extract 2 marker and 3 sample out of 166 marker and 3 sample Tue Dec 2 14:49:32 2025 - read bed Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim and dimnames Tue Dec 2 14:49:32 2025 - end --------------- test openPlink --------------- --------------- test readPlinkBySubscript --------------- start file = D:/RCompile/CRANpkg/lib/4.6/seqminer/plink/all.anno.filtered.extract.bed extract 2 marker and 3 sample out of 166 marker and 3 sample Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim Tue Dec 2 14:49:32 2025 - end --------------- test readSingleChromosomeVCFToMatrixByRange --------------- fsize = 2688 query [0, 0] Found 1 results found 1 position, e.g. 0 2384 Inferred 3 samples from header 1 region to be extracted. query [196621007, 196716634] Found 166 results found 166 position, e.g. 1.96623e+08 2454 --------------- test createSingleChromosomeVCFIndex --------------- header line has 3 samples offset = 2384 Indexing finished with 3 samples and 166 markers created index file [ D:\temp\2025_12_02_01_50_00_12944\RtmpMBdQl9\filef27c6f9a5b14 ] Saving _problems/test-vcf-167.R --------------- test readSingleChromosomeBCFToMatrixByRange --------------- fsize = 2688 l_text = 4206 Total contig parse = 1, total header index used = 47 Inferred 3 samples from header 1 region to be extracted. query [196621006, 196716633] Found 166 results 1.96623e+08 4215 found 166 position, e.g. 1.96623e+08 4215 sampleNames.size() = 3, markerNames.size() = 166 --------------- test createSingleChromosomeBCFIndex --------------- l_text = 4206 Total contig parse = 1, total header index used = 47 offset_header = 4135 sample size = 3 last character is s[after_chrom_size-1] = 0 Indexing finished with 3 samples and 166 markers created index file [ D:\temp\2025_12_02_01_50_00_12944\RtmpMBdQl9\filef27c665d13af ] Saving _problems/test-vcf-181.R [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] ══ Failed tests ════════════════════════════════════════════════════════════════ ── Error ('test-vcf.R:167:5'): createSingleChromosomeVCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:167:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) ── Error ('test-vcf.R:181:5'): createSingleChromosomeBCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:181:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] Error: ! Test failures. Execution halted Flavor: r-devel-windows-x86_64

Version: 9.7
Check: tests
Result: ERROR Running ‘testthat.R’ [2s/5s] Running the tests in ‘tests/testthat.R’ failed. Complete output: > ## follow http://adv-r.had.co.nz/Testing.html > print(sprintf("Test seqminer [version %s]", packageVersion("seqminer"))) [1] "Test seqminer [version 9.7]" > print("Platform") [1] "Platform" > print(str(.Platform)) List of 8 $ OS.type : chr "unix" $ file.sep : chr "/" $ dynlib.ext: chr ".so" $ GUI : chr "X11" $ endian : chr "little" $ pkgType : chr "source" $ path.sep : chr ":" $ r_arch : chr "" NULL > > print("Sys.info()") [1] "Sys.info()" > print(Sys.info()) sysname "Linux" release "6.12.22-amd64" version "#1 SMP PREEMPT_DYNAMIC Debian 6.12.22-1 (2025-04-10)" nodename "gimli2" machine "x86_64" login "hornik" user "hornik" effective_user "hornik" > > print(citation("seqminer")) To cite package 'seqminer' in publications use: Zhan X, Liu D (2015). "SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations." _Genetic Epidemiology_, *39*(8), 1242. doi:10.1002/gepi.21918 <https://doi.org/10.1002/gepi.21918>, seqminer version 9.7, <http://dx.doi.org/10.1002/gepi.21918>. A BibTeX entry for LaTeX users is @Article{, title = {SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations}, author = {Xiaowei Zhan and Dajiang J Liu}, journal = {Genetic Epidemiology}, volume = {39}, number = {8}, pages = {1242}, year = {2015}, note = {seqminer version 9.7}, web = {http:/zhanxw.github.io/seqminer}, publisher = {Wiley Online Library}, url = {http://dx.doi.org/10.1002/gepi.21918}, doi = {10.1002/gepi.21918}, } > > library(testthat) > library(seqminer) > ## ## test code are under inst/tests > ## ## test_package("seqminer", reporter="tap") > ## test_package("seqminer") > test_check("seqminer") 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/bi.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/bi.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:2" "1:3" [[1]] [1] "G" "G" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 Skipped: encounter a duplicated site: [ 1:1 ] in file [ /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:3" [[1]] [1] "T" "G" [[1]] [,1] [,2] [1,] 0.1993610 -0.0284801 [2,] -0.0284801 0.1139210 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1_A/G" "1:1_A/T" "1:3_A/G" [[1]] [1] "G" "T" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 [1] "=============" Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:1/1 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:1/1 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 [1] "=============" $pos [1] 1 2 3 $ref [1] "A" "A" "A" $alt [1] "G" "G" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" $pos [1] 1 1 3 $ref [1] "A" "A" "A" $alt [1] "G" "T" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" Skipped: encounter a duplicated site: [ 1:1 ] in file [ /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. Loading objects: apoe cfh cfh.all cfh.nonsyn cfh.nonsyn.2 cfh.range cfh.syn cfh.syn.2 out.gene.1 out.gene.2 out.gene.3 out.range.1 ssss --------------- test readVCFToMatrixByRange --------------- 1 region to be extracted. 1 region to be extracted. 2 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] 1 region to be extracted. range of [ APOE ] is [ 19:45409038-45412650 ] 1 region to be extracted. range of [ ssss ] is [ ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 1 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 start file = /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/plink/all.anno.filtered.extract Wed Dec 3 19:34:58 2025 - read bim Wed Dec 3 19:34:58 2025 - read fam extract 2 marker and 3 sample out of 166 marker and 3 sample Wed Dec 3 19:34:58 2025 - read bed Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim and dimnames Wed Dec 3 19:34:58 2025 - end --------------- test openPlink --------------- --------------- test readPlinkBySubscript --------------- start file = /home/hornik/tmp/R.check/r-patched-gcc/Work/build/Packages/seqminer/plink/all.anno.filtered.extract.bed extract 2 marker and 3 sample out of 166 marker and 3 sample Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim Wed Dec 3 19:34:58 2025 - end --------------- test readSingleChromosomeVCFToMatrixByRange --------------- fsize = 2688 query [0, 0] Found 1 results found 1 position, e.g. 0 2384 Inferred 3 samples from header 1 region to be extracted. query [196621007, 196716634] Found 166 results found 166 position, e.g. 196623337 2454 --------------- test createSingleChromosomeVCFIndex --------------- header line has 3 samples offset = 2384 Indexing finished with 3 samples and 166 markers created index file [ /home/hornik/tmp/scratch/RtmpE7bLvc/file20ca0d7b1b68c4 ] Saving _problems/test-vcf-167.R --------------- test readSingleChromosomeBCFToMatrixByRange --------------- fsize = 2688 l_text = 4206 Total contig parse = 1, total header index used = 47 Inferred 3 samples from header 1 region to be extracted. query [196621006, 196716633] Found 166 results 196623336 4215 found 166 position, e.g. 196623336 4215 sampleNames.size() = 3, markerNames.size() = 166 --------------- test createSingleChromosomeBCFIndex --------------- l_text = 4206 Total contig parse = 1, total header index used = 47 offset_header = 4135 sample size = 3 last character is s[after_chrom_size-1] = 0 Indexing finished with 3 samples and 166 markers created index file [ /home/hornik/tmp/scratch/RtmpE7bLvc/file20ca0d3fa23cff ] Saving _problems/test-vcf-181.R [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] ══ Failed tests ════════════════════════════════════════════════════════════════ ── Error ('test-vcf.R:167:5'): createSingleChromosomeVCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:167:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) ── Error ('test-vcf.R:181:5'): createSingleChromosomeBCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:181:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] Error: ! Test failures. Execution halted Flavor: r-patched-linux-x86_64

Version: 9.7
Check: tests
Result: ERROR Running ‘testthat.R’ [3s/4s] Running the tests in ‘tests/testthat.R’ failed. Complete output: > ## follow http://adv-r.had.co.nz/Testing.html > print(sprintf("Test seqminer [version %s]", packageVersion("seqminer"))) [1] "Test seqminer [version 9.7]" > print("Platform") [1] "Platform" > print(str(.Platform)) List of 8 $ OS.type : chr "unix" $ file.sep : chr "/" $ dynlib.ext: chr ".so" $ GUI : chr "X11" $ endian : chr "little" $ pkgType : chr "source" $ path.sep : chr ":" $ r_arch : chr "" NULL > > print("Sys.info()") [1] "Sys.info()" > print(Sys.info()) sysname "Linux" release "6.12.22-amd64" version "#1 SMP PREEMPT_DYNAMIC Debian 6.12.22-1 (2025-04-10)" nodename "gimli2" machine "x86_64" login "hornik" user "hornik" effective_user "hornik" > > print(citation("seqminer")) To cite package 'seqminer' in publications use: Zhan X, Liu D (2015). "SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations." _Genetic Epidemiology_, *39*(8), 1242. doi:10.1002/gepi.21918 <https://doi.org/10.1002/gepi.21918>, seqminer version 9.7, <http://dx.doi.org/10.1002/gepi.21918>. A BibTeX entry for LaTeX users is @Article{, title = {SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations}, author = {Xiaowei Zhan and Dajiang J Liu}, journal = {Genetic Epidemiology}, volume = {39}, number = {8}, pages = {1242}, year = {2015}, note = {seqminer version 9.7}, web = {http:/zhanxw.github.io/seqminer}, publisher = {Wiley Online Library}, url = {http://dx.doi.org/10.1002/gepi.21918}, doi = {10.1002/gepi.21918}, } > > library(testthat) > library(seqminer) > ## ## test code are under inst/tests > ## ## test_package("seqminer", reporter="tap") > ## test_package("seqminer") > test_check("seqminer") 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/bi.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/bi.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:2" "1:3" [[1]] [1] "G" "G" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 Skipped: encounter a duplicated site: [ 1:1 ] in file [ /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:3" [[1]] [1] "T" "G" [[1]] [,1] [,2] [1,] 0.1993610 -0.0284801 [2,] -0.0284801 0.1139210 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1_A/G" "1:1_A/T" "1:3_A/G" [[1]] [1] "G" "T" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 [1] "=============" Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:1/1 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:1/1 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 [1] "=============" $pos [1] 1 2 3 $ref [1] "A" "A" "A" $alt [1] "G" "G" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" $pos [1] 1 1 3 $ref [1] "A" "A" "A" $alt [1] "G" "T" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" Skipped: encounter a duplicated site: [ 1:1 ] in file [ /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. Loading objects: apoe cfh cfh.all cfh.nonsyn cfh.nonsyn.2 cfh.range cfh.syn cfh.syn.2 out.gene.1 out.gene.2 out.gene.3 out.range.1 ssss --------------- test readVCFToMatrixByRange --------------- 1 region to be extracted. 1 region to be extracted. 2 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] 1 region to be extracted. range of [ APOE ] is [ 19:45409038-45412650 ] 1 region to be extracted. range of [ ssss ] is [ ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 1 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 start file = /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/plink/all.anno.filtered.extract Sat Nov 29 19:35:02 2025 - read bim Sat Nov 29 19:35:02 2025 - read fam extract 2 marker and 3 sample out of 166 marker and 3 sample Sat Nov 29 19:35:02 2025 - read bed Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim and dimnames Sat Nov 29 19:35:02 2025 - end --------------- test openPlink --------------- --------------- test readPlinkBySubscript --------------- start file = /home/hornik/tmp/R.check/r-release-gcc/Work/build/Packages/seqminer/plink/all.anno.filtered.extract.bed extract 2 marker and 3 sample out of 166 marker and 3 sample Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim Sat Nov 29 19:35:02 2025 - end --------------- test readSingleChromosomeVCFToMatrixByRange --------------- fsize = 2688 query [0, 0] Found 1 results found 1 position, e.g. 0 2384 Inferred 3 samples from header 1 region to be extracted. query [196621007, 196716634] Found 166 results found 166 position, e.g. 196623337 2454 --------------- test createSingleChromosomeVCFIndex --------------- header line has 3 samples offset = 2384 Indexing finished with 3 samples and 166 markers created index file [ /home/hornik/tmp/scratch/RtmpdLn4FM/file2926a76e72b3c2 ] Saving _problems/test-vcf-167.R --------------- test readSingleChromosomeBCFToMatrixByRange --------------- fsize = 2688 l_text = 4206 Total contig parse = 1, total header index used = 47 Inferred 3 samples from header 1 region to be extracted. query [196621006, 196716633] Found 166 results 196623336 4215 found 166 position, e.g. 196623336 4215 sampleNames.size() = 3, markerNames.size() = 166 --------------- test createSingleChromosomeBCFIndex --------------- l_text = 4206 Total contig parse = 1, total header index used = 47 offset_header = 4135 sample size = 3 last character is s[after_chrom_size-1] = 0 Indexing finished with 3 samples and 166 markers created index file [ /home/hornik/tmp/scratch/RtmpdLn4FM/file2926a717ed7e54 ] Saving _problems/test-vcf-181.R [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] ══ Failed tests ════════════════════════════════════════════════════════════════ ── Error ('test-vcf.R:167:5'): createSingleChromosomeVCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:167:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) ── Error ('test-vcf.R:181:5'): createSingleChromosomeBCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:181:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] Error: ! Test failures. Execution halted Flavor: r-release-linux-x86_64

Version: 9.7
Check: whether package can be installed
Result: WARN Found the following significant warnings: SingleChromosomeVCFIndex.cpp:109:51: warning: format specifies type 'long' but the argument has type 'int64_t' (aka 'long long') [-Wformat] See ‘/Volumes/Builds/packages/big-sur-x86_64/results/4.5/seqminer.Rcheck/00install.out’ for details. * used C compiler: ‘Apple clang version 14.0.3 (clang-1403.0.22.14.1)’ * used C++ compiler: ‘Apple clang version 14.0.3 (clang-1403.0.22.14.1)’ * used SDK: ‘MacOSX11.3.sdk’ Flavor: r-release-macos-x86_64

Version: 9.7
Check: tests
Result: ERROR Running 'testthat.R' [3s] Running the tests in 'tests/testthat.R' failed. Complete output: > ## follow http://adv-r.had.co.nz/Testing.html > print(sprintf("Test seqminer [version %s]", packageVersion("seqminer"))) [1] "Test seqminer [version 9.7]" > print("Platform") [1] "Platform" > print(str(.Platform)) List of 8 $ OS.type : chr "windows" $ file.sep : chr "/" $ dynlib.ext: chr ".dll" $ GUI : chr "RTerm" $ endian : chr "little" $ pkgType : chr "win.binary" $ path.sep : chr ";" $ r_arch : chr "x64" NULL > > print("Sys.info()") [1] "Sys.info()" > print(Sys.info()) sysname release version nodename machine "Windows" "Server x64" "build 20348" "CRANWIN3" "x86-64" login user effective_user udomain "CRAN" "CRAN" "CRAN" "CRANWIN3" > > print(citation("seqminer")) To cite package 'seqminer' in publications use: Zhan X, Liu D (2015). "SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations." _Genetic Epidemiology_, *39*(8), 1242. doi:10.1002/gepi.21918 <https://doi.org/10.1002/gepi.21918>, seqminer version 9.7, <http://dx.doi.org/10.1002/gepi.21918>. A BibTeX entry for LaTeX users is @Article{, title = {SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations}, author = {Xiaowei Zhan and Dajiang J Liu}, journal = {Genetic Epidemiology}, volume = {39}, number = {8}, pages = {1242}, year = {2015}, note = {seqminer version 9.7}, web = {http:/zhanxw.github.io/seqminer}, publisher = {Wiley Online Library}, url = {http://dx.doi.org/10.1002/gepi.21918}, doi = {10.1002/gepi.21918}, } > > library(testthat) > library(seqminer) > ## ## test code are under inst/tests > ## ## test_package("seqminer", reporter="tap") > ## test_package("seqminer") > test_check("seqminer") 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/bi.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/bi.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:2" "1:3" [[1]] [1] "G" "G" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 Skipped: encounter a duplicated site: [ 1:1 ] in file [ D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/tri.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/tri.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:3" [[1]] [1] "T" "G" [[1]] [,1] [,2] [1,] 0.1993610 -0.0284801 [2,] -0.0284801 0.1139210 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1_A/G" "1:1_A/T" "1:3_A/G" [[1]] [1] "G" "T" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 [1] "=============" Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:1/1 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:1/1 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 [1] "=============" $pos [1] 1 2 3 $ref [1] "A" "A" "A" $alt [1] "G" "G" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" $pos [1] 1 1 3 $ref [1] "A" "A" "A" $alt [1] "G" "T" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" Skipped: encounter a duplicated site: [ 1:1 ] in file [ D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: D:/RCompile/CRANpkg/lib/4.5/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. Loading objects: apoe cfh cfh.all cfh.nonsyn cfh.nonsyn.2 cfh.range cfh.syn cfh.syn.2 out.gene.1 out.gene.2 out.gene.3 out.range.1 ssss --------------- test readVCFToMatrixByRange --------------- 1 region to be extracted. 1 region to be extracted. 2 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] 1 region to be extracted. range of [ APOE ] is [ 19:45409038-45412650 ] 1 region to be extracted. range of [ ssss ] is [ ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 1 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 start file = D:/RCompile/CRANpkg/lib/4.5/seqminer/plink/all.anno.filtered.extract Sun Nov 16 02:55:57 2025 - read bim Sun Nov 16 02:55:57 2025 - read fam extract 2 marker and 3 sample out of 166 marker and 3 sample Sun Nov 16 02:55:57 2025 - read bed Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim and dimnames Sun Nov 16 02:55:57 2025 - end --------------- test openPlink --------------- --------------- test readPlinkBySubscript --------------- start file = D:/RCompile/CRANpkg/lib/4.5/seqminer/plink/all.anno.filtered.extract.bed extract 2 marker and 3 sample out of 166 marker and 3 sample Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim Sun Nov 16 02:55:57 2025 - end --------------- test readSingleChromosomeVCFToMatrixByRange --------------- fsize = 2688 query [0, 0] Found 1 results found 1 position, e.g. 0 2384 Inferred 3 samples from header 1 region to be extracted. query [196621007, 196716634] Found 166 results found 166 position, e.g. 1.96623e+08 2454 --------------- test createSingleChromosomeVCFIndex --------------- header line has 3 samples offset = 2384 Indexing finished with 3 samples and 166 markers created index file [ D:\temp\2025_11_15_13_34_13_7498\RtmpUbmiGA\fileeedc1db21f4a ] Saving _problems/test-vcf-167.R --------------- test readSingleChromosomeBCFToMatrixByRange --------------- fsize = 2688 l_text = 4206 Total contig parse = 1, total header index used = 47 Inferred 3 samples from header 1 region to be extracted. query [196621006, 196716633] Found 166 results 1.96623e+08 4215 found 166 position, e.g. 1.96623e+08 4215 sampleNames.size() = 3, markerNames.size() = 166 --------------- test createSingleChromosomeBCFIndex --------------- l_text = 4206 Total contig parse = 1, total header index used = 47 offset_header = 4135 sample size = 3 last character is s[after_chrom_size-1] = 0 Indexing finished with 3 samples and 166 markers created index file [ D:\temp\2025_11_15_13_34_13_7498\RtmpUbmiGA\fileeedc43f3d58 ] Saving _problems/test-vcf-181.R [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] ══ Failed tests ════════════════════════════════════════════════════════════════ ── Error ('test-vcf.R:167:5'): createSingleChromosomeVCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:167:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) ── Error ('test-vcf.R:181:5'): createSingleChromosomeBCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:181:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] Error: ! Test failures. Execution halted Flavor: r-release-windows-x86_64

Version: 9.7
Check: installed package size
Result: NOTE installed size is 19.3Mb sub-directories of 1Mb or more: libs 17.8Mb Flavors: r-oldrel-macos-arm64, r-oldrel-macos-x86_64

Version: 9.7
Check: for GNU extensions in Makefiles
Result: NOTE GNU make is a SystemRequirements. Flavors: r-oldrel-macos-arm64, r-oldrel-macos-x86_64, r-oldrel-windows-x86_64

Version: 9.7
Check: whether package can be installed
Result: WARN Found the following significant warnings: SingleChromosomeVCFIndex.cpp:109:51: warning: format specifies type 'long' but the argument has type 'int64_t' (aka 'long long') [-Wformat] See ‘/Volumes/Builds/packages/big-sur-x86_64/results/4.4/seqminer.Rcheck/00install.out’ for details. * used C compiler: ‘Apple clang version 14.0.3 (clang-1403.0.22.14.1)’ * used C++ compiler: ‘Apple clang version 14.0.3 (clang-1403.0.22.14.1)’ * used SDK: ‘MacOSX11.3.sdk’ Flavor: r-oldrel-macos-x86_64

Version: 9.7
Check: tests
Result: ERROR Running 'testthat.R' [4s] Running the tests in 'tests/testthat.R' failed. Complete output: > ## follow http://adv-r.had.co.nz/Testing.html > print(sprintf("Test seqminer [version %s]", packageVersion("seqminer"))) [1] "Test seqminer [version 9.7]" > print("Platform") [1] "Platform" > print(str(.Platform)) List of 8 $ OS.type : chr "windows" $ file.sep : chr "/" $ dynlib.ext: chr ".dll" $ GUI : chr "RTerm" $ endian : chr "little" $ pkgType : chr "win.binary" $ path.sep : chr ";" $ r_arch : chr "x64" NULL > > print("Sys.info()") [1] "Sys.info()" > print(Sys.info()) sysname release version nodename machine "Windows" "Server x64" "build 20348" "CRANWIN2" "x86-64" login user effective_user "CRAN" "CRAN" "CRAN" > > print(citation("seqminer")) To cite package 'seqminer' in publications use: Zhan X, Liu D (2015). "SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations." _Genetic Epidemiology_, *39*(8), 1242. doi:10.1002/gepi.21918 <https://doi.org/10.1002/gepi.21918>, seqminer version 9.7, <http://dx.doi.org/10.1002/gepi.21918>. A BibTeX entry for LaTeX users is @Article{, title = {SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations}, author = {Xiaowei Zhan and Dajiang J Liu}, journal = {Genetic Epidemiology}, volume = {39}, number = {8}, pages = {1242}, year = {2015}, note = {seqminer version 9.7}, web = {http:/zhanxw.github.io/seqminer}, publisher = {Wiley Online Library}, url = {http://dx.doi.org/10.1002/gepi.21918}, doi = {10.1002/gepi.21918}, } > > library(testthat) > library(seqminer) > ## ## test code are under inst/tests > ## ## test_package("seqminer", reporter="tap") > ## test_package("seqminer") > test_check("seqminer") 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/bi.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/bi.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:2" "1:3" [[1]] [1] "G" "G" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 Skipped: encounter a duplicated site: [ 1:1 ] in file [ D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/tri.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/tri.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1" "1:3" [[1]] [1] "T" "G" [[1]] [,1] [,2] [1,] 0.1993610 -0.0284801 [2,] -0.0284801 0.1139210 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/tri.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/tri.MetaCov.assoc.gz Finished calculation. [1] "1:1_A/G" "1:1_A/T" "1:3_A/G" [[1]] [1] "G" "T" "G" [[1]] [,1] [,2] [,3] [1,] 0.5126420 -0.0427202 0.0427202 [2,] -0.0427202 0.1993610 -0.0284801 [3,] 0.0427202 -0.0284801 0.1139210 [1] "=============" Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 1:1 1:2 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:2 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 Total 3 line loaded, now put them to matrix [ 3 x 3 ] in R ... 1:1 1:1/1 1:3 1:1 0.5126420 -0.0427202 0.0427202 1:1/1 -0.0427202 0.1993610 -0.0284801 1:3 0.0427202 -0.0284801 0.1139210 [1] "=============" $pos [1] 1 2 3 $ref [1] "A" "A" "A" $alt [1] "G" "G" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" $pos [1] 1 1 3 $ref [1] "A" "A" "A" $alt [1] "G" "T" "G" $nSample [1] 9 9 9 $af [1] 0.3333330 0.1111110 0.0555556 $ac [1] 6 2 1 $callRate [1] 1 1 1 $hwe [1] "1" "1" "1" $nref [1] 4 7 8 $nhet [1] 4 2 1 $nalt [1] 1 0 0 $ustat [1] 0.283603 0.000000 0.325521 $vstat [1] 2.14797 1.33950 1.01256 $effect [1] 0.0614687 0.0000000 0.3174930 $pVal [1] 0.894958 1.000000 0.747845 $anno [1] "" "" "" $annoFull [1] "" "" "" Skipped: encounter a duplicated site: [ 1:1 ] in file [ D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ] 1 gene/region to be extracted. Read score tests... In study 0 Error: encounter a duplicated location: [ 1:1 ] in file [ D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz ], will overwrite previous results! Done read score file: D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. 1 gene/region to be extracted. Read score tests... In study 0 Done read score file: D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/test2.study1.MetaScore.assoc.gz In study 1 Done read score file: D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/test2.study2.MetaScore.assoc.gz Read cov files ... In study 0 Done read cov file: D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/test2.study1.MetaCov.assoc.gz In study 1 Done read cov file: D:/RCompile/CRANpkg/lib/4.4/seqminer/test-triallelic/test2.study2.MetaCov.assoc.gz Finished calculation. Loading objects: apoe cfh cfh.all cfh.nonsyn cfh.nonsyn.2 cfh.range cfh.syn cfh.syn.2 out.gene.1 out.gene.2 out.gene.3 out.range.1 ssss --------------- test readVCFToMatrixByRange --------------- 1 region to be extracted. 1 region to be extracted. 2 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] 1 region to be extracted. range of [ APOE ] is [ 19:45409038-45412650 ] 1 region to be extracted. range of [ ssss ] is [ ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 1 region to be extracted. 1 region to be extracted. 1 region to be extracted. range of [ CFH ] is [ 1:196621007-196716634 ] range of [ CFH ] is [ 1:196621007-196716634 ] range = 1:196621007-196716634 start file = D:/RCompile/CRANpkg/lib/4.4/seqminer/plink/all.anno.filtered.extract Wed Dec 3 21:53:05 2025 - read bim Wed Dec 3 21:53:05 2025 - read fam extract 2 marker and 3 sample out of 166 marker and 3 sample Wed Dec 3 21:53:05 2025 - read bed Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim and dimnames Wed Dec 3 21:53:05 2025 - end --------------- test openPlink --------------- --------------- test readPlinkBySubscript --------------- start file = D:/RCompile/CRANpkg/lib/4.4/seqminer/plink/all.anno.filtered.extract.bed extract 2 marker and 3 sample out of 166 marker and 3 sample Binary PLINK BED file is ready to read build a look-up table assigned 6 values allocate dim Wed Dec 3 21:53:05 2025 - end --------------- test readSingleChromosomeVCFToMatrixByRange --------------- fsize = 2688 query [0, 0] Found 1 results found 1 position, e.g. 0 2384 Inferred 3 samples from header 1 region to be extracted. query [196621007, 196716634] Found 166 results found 166 position, e.g. 1.96623e+08 2454 --------------- test createSingleChromosomeVCFIndex --------------- header line has 3 samples offset = 2384 Indexing finished with 3 samples and 166 markers created index file [ D:\temp\2025_12_03_01_50_00_178\Rtmp8mjxO2\file7810628677ba ] Saving _problems/test-vcf-167.R --------------- test readSingleChromosomeBCFToMatrixByRange --------------- fsize = 2688 l_text = 4206 Total contig parse = 1, total header index used = 47 Inferred 3 samples from header 1 region to be extracted. query [196621006, 196716633] Found 166 results 1.96623e+08 4215 found 166 position, e.g. 1.96623e+08 4215 sampleNames.size() = 3, markerNames.size() = 166 --------------- test createSingleChromosomeBCFIndex --------------- l_text = 4206 Total contig parse = 1, total header index used = 47 offset_header = 4135 sample size = 3 last character is s[after_chrom_size-1] = 0 Indexing finished with 3 samples and 166 markers created index file [ D:\temp\2025_12_03_01_50_00_178\Rtmp8mjxO2\file781056414e7 ] Saving _problems/test-vcf-181.R [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] ══ Failed tests ════════════════════════════════════════════════════════════════ ── Error ('test-vcf.R:167:5'): createSingleChromosomeVCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:167:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) ── Error ('test-vcf.R:181:5'): createSingleChromosomeBCFIndex ────────────────── Error in `expect(nchar(cfh) > 0)`: `failure_message` must be a character vector, not absent. Backtrace: ▆ 1. └─testthat::expect(failure_message = <empty>) at test-vcf.R:181:5 2. └─testthat:::check_character(failure_message) 3. └─testthat:::stop_input_type(...) 4. └─rlang::abort(message, ..., call = call, arg = arg) [ FAIL 2 | WARN 0 | SKIP 0 | PASS 72 ] Error: ! Test failures. Execution halted Flavor: r-oldrel-windows-x86_64

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