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biospear: Biomarker Selection in Penalized Regression Models

Provides some tools for developing and validating prediction models, estimate expected survival of patients and visualize them graphically. Most of the implemented methods are based on penalized regressions such as: the lasso (Tibshirani R (1996)), the elastic net (Zou H et al. (2005) <doi:10.1111/j.1467-9868.2005.00503.x>), the adaptive lasso (Zou H (2006) <doi:10.1198/016214506000000735>), the stability selection (Meinshausen N et al. (2010) <doi:10.1111/j.1467-9868.2010.00740.x>), some extensions of the lasso (Ternes et al. (2016) <doi:10.1002/sim.6927>), some methods for the interaction setting (Ternes N et al. (2016) <doi:10.1002/bimj.201500234>), or others. A function generating simulated survival data set is also provided.

Version: 1.0.2
Depends: R (≥ 2.10), pkgconfig
Imports: cobs, corpcor, devtools, glmnet, graphics, grplasso, MASS, Matrix, mboost, parallel, plsRcox, pROC, PRROC, RCurl, stats, survAUC, survival
Published: 2018-12-04
Author: Nils Ternes [aut], Federico Rotolo [aut], Stefan Michiels [aut, cre]
Maintainer: Stefan Michiels <stefan.michiels at gustaveroussy.fr>
License: GPL-2
NeedsCompilation: no
CRAN checks: biospear results

Documentation:

Reference manual: biospear.pdf

Downloads:

Package source: biospear_1.0.2.tar.gz
Windows binaries: r-devel: biospear_1.0.2.zip, r-release: biospear_1.0.2.zip, r-oldrel: biospear_1.0.2.zip
macOS binaries: r-release (arm64): biospear_1.0.2.tgz, r-oldrel (arm64): biospear_1.0.2.tgz, r-release (x86_64): biospear_1.0.2.tgz, r-oldrel (x86_64): biospear_1.0.2.tgz
Old sources: biospear archive

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
Health stats visible at Monitor.