bioLeak: Leakage-Safe Modeling and Auditing for Genomic and Clinical Data

Prevents and detects information leakage in biomedical machine learning. Provides leakage-resistant split policies (subject-grouped, batch-blocked, study leave-out, time-ordered), guarded preprocessing (train-only imputation, normalization, filtering, feature selection), cross-validated fitting with common learners, permutation-gap auditing, batch and fold association tests, and duplicate detection.

Version:	0.1.0
Depends:	R (≥ 4.3)
Imports:	digest, methods, stats, utils, SummarizedExperiment, graphics, hardhat, parsnip
Suggests:	BiocParallel, cli, dials, FNN, future, future.apply, ggplot2, glmnet, mice, missForest, pkgload, ranger, randomForest, recipes, RANN, rsample, tune, VIM, workflows, xgboost, yardstick, pROC, PRROC, survival, knitr, rmarkdown, testthat (≥ 3.0.0)
Published:	2026-02-06
DOI:	10.32614/CRAN.package.bioLeak
Author:	Selcuk Korkmaz [aut, cre]
Maintainer:	Selcuk Korkmaz <selcukorkmaz at gmail.com>
BugReports:	https://github.com/selcukorkmaz/bioLeak/issues
License:	MIT + file LICENSE
URL:	https://github.com/selcukorkmaz/bioLeak
NeedsCompilation:	no
Materials:	README
CRAN checks:	bioLeak results [issues need fixing before 2026-03-01]

Documentation:

Reference manual:	bioLeak.html , bioLeak.pdf
Vignettes:	bioLeak: Leakage-Aware Biomedical Modeling (source, R code)

Downloads:

Package source:	bioLeak_0.1.0.tar.gz
Windows binaries:	r-devel: bioLeak_0.1.0.zip, r-release: not available, r-oldrel: not available
macOS binaries:	r-release (arm64): bioLeak_0.1.0.tgz, r-oldrel (arm64): bioLeak_0.1.0.tgz, r-release (x86_64): bioLeak_0.1.0.tgz, r-oldrel (x86_64): bioLeak_0.1.0.tgz

Linking:

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