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UKBAnalytica: UK Biobank Data Processing and Survival Analysis Toolkit

Provides an integrated workflow for UK Biobank Research Analysis Platform (RAP) hosted and RAP-generated analysis tables. The package supports RAP phenotype extraction planning, predefined variable sets and disease definitions, standardized baseline preprocessing, multi-source endpoint ascertainment, prevalent and incident case classification, survival-ready cohort construction, regression, multiple imputation, propensity score analysis, mediation analysis, subgroup and sensitivity analyses, machine learning, proteomics enrichment and protein-protein interaction analysis, and publication-oriented visualization. The package workflow is described in He et al. (2026) <doi:10.64898/2026.06.19.26356057>.

Version: 1.0.0
Depends: R (≥ 4.0)
Imports: data.table, stringi, ggplot2, rlang, scales, survival, pROC, tableone, mice, mitools, sandwich, lmtest, MASS, mgcv, xml2, igraph
Suggests: testthat, rms, gbm, cobalt, survminer, MatchIt, regmedint, ranger, xgboost, glmnet, e1071, nnet, rpart, Boruta, rBayesianOptimization, randomForestSRC, clusterProfiler, AnnotationDbi, org.Hs.eg.db, qs2
Published: 2026-06-30
DOI: 10.32614/CRAN.package.UKBAnalytica (may not be active yet)
Author: Nan He ORCID iD [aut, cre]
Maintainer: Nan He <hinna01 at 163.com>
BugReports: https://github.com/Hinna0818/UKBAnalytica/issues
License: MIT + file LICENSE
URL: https://github.com/Hinna0818/UKBAnalytica, https://hinna0818.github.io/UKBAnalytica/
NeedsCompilation: no
Materials: NEWS
CRAN checks: UKBAnalytica results

Documentation:

Reference manual: UKBAnalytica.html , UKBAnalytica.pdf

Downloads:

Package source: UKBAnalytica_1.0.0.tar.gz
Windows binaries: r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): UKBAnalytica_1.0.0.tgz, r-oldrel (arm64): UKBAnalytica_1.0.0.tgz, r-release (x86_64): UKBAnalytica_1.0.0.tgz, r-oldrel (x86_64): UKBAnalytica_1.0.0.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=UKBAnalytica to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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