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MosaiClusteR: An Umbrella Framework for Multi-Source and Multi-Omics Clustering

An umbrella framework ("MoSaIC" = Multi-Omics Source-Agnostic Integration Clustering in R) that unifies a large collection of multi-source / multi-omics clustering methodologies behind a single, consistent list-of-matrices interface. It spans five integration paradigms - direct, similarity-based, graph-based, voting-based consensus, and hierarchy-based - and bundles a complete downstream workflow for method comparison and evaluation. The package features the multi-source the ability to compare many algorithms on the same footing, a data-nugget based feature-weighting scheme as a robust, big-data-friendly alternative to variance weighting, and a downstream suite for cluster characterisation, visualisation and biological interpretation.

Version: 0.1.0
Depends: R (≥ 4.0)
Imports: stats, utils, methods, graphics, grDevices, cluster, fastcluster, matrixStats, FD, ade4, e1071, gtools, data.table, Rcpp, Rdpack
LinkingTo: Rcpp
Suggests: SNFtool, datanugget, WCluster, LUCIDus, igraph, lsa, analogue, FactoMineR, pls, circlize, gplots, dendextend, plotrix, limma, MLP, biomaRt, org.Hs.eg.db, Biobase, a4Core, a4Base, plyr, genefilter, ggplot2, gridExtra, uwot, Rtsne, MOFAdata, testthat (≥ 3.0.0), knitr, rmarkdown
Published: 2026-07-29
DOI: 10.32614/CRAN.package.MosaiClusteR
Author: Bernard Isekah Osang'ir ORCID iD [aut, cre], Marijke Van Moerbeke [aut], Ziv Shkedy [ctb], Surya Gupta [ctb], Jürgen Claesen [ctb]
Maintainer: Bernard Isekah Osang'ir <bernard.osangir at sckcen.be>
BugReports: https://github.com/lucp12891/MosaiClusteR/issues
License: GPL-3
URL: https://github.com/lucp12891/MosaiClusteR
NeedsCompilation: yes
Citation: MosaiClusteR citation info
Materials: README, NEWS
CRAN checks: MosaiClusteR results

Documentation:

Reference manual: MosaiClusteR.html , MosaiClusteR.pdf
Vignettes: MosaiClusteR: an umbrella framework for multi-source and multi-omics clustering (source, R code)

Downloads:

Package source: MosaiClusteR_0.1.0.tar.gz
Windows binaries: r-devel: MosaiClusteR_0.1.0.zip, r-release: MosaiClusteR_0.1.0.zip, r-oldrel: MosaiClusteR_0.1.0.zip
macOS binaries: r-release (arm64): MosaiClusteR_0.1.0.tgz, r-oldrel (arm64): MosaiClusteR_0.1.0.tgz, r-release (x86_64): MosaiClusteR_0.1.0.tgz, r-oldrel (x86_64): MosaiClusteR_0.1.0.tgz

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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