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uncertR: Bootstrap Prediction Uncertainty and Its Biological Drivers in Gene-Expression Models

Fits bootstrap ensembles of penalized regression models on bulk gene-expression data, derives per-sample uncertainty scores from out-of-bag predictions, and tests whether technical covariates explain that uncertainty. The bootstrap method is described by Efron and Tibshirani (1993, ISBN:9780412042317), and elastic-net regression follows Friedman, Hastie, and Tibshirani (2010) <doi:10.18637/jss.v033.i01>. The optional immunedeconv package, used for immune-cell deconvolution, is available from GitHub <https://github.com/omnideconv/immunedeconv>.

Version: 0.1.3
Depends: R (≥ 4.2.0)
Imports: glmnet, future.apply, splines, stats, graphics
Suggests: testthat (≥ 3.0.0), SummarizedExperiment, knitr, rmarkdown, immunedeconv
Published: 2026-11-03
DOI: 10.32614/CRAN.package.uncertR
Author: Tanay Belapurkar [aut, cre]
Maintainer: Tanay Belapurkar <btanay041 at gmail.com>
License: MIT + file LICENSE
NeedsCompilation: no
CRAN checks: uncertR results

Documentation:

Reference manual: uncertR.html , uncertR.pdf
Vignettes: Getting started with uncertR (source)

Downloads:

Package source: uncertR_0.1.3.tar.gz
Windows binaries: r-devel: uncertR_0.1.3.zip, r-release: uncertR_0.1.3.zip, r-oldrel: uncertR_0.1.3.zip
macOS binaries: r-release (arm64): uncertR_0.1.3.tgz, r-oldrel (arm64): uncertR_0.1.3.tgz, r-release (x86_64): uncertR_0.1.3.tgz, r-oldrel (x86_64): uncertR_0.1.3.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=uncertR to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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