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titeIR: Isotonic Designs for Phase 1 Trials with Late-Onset Toxicities

Functions to design phase 1 trials using an isotonic regression based design incorporating time-to-event information. Simulation and design functions are available, which incorporate information about followup and DLTs, and apply isotonic regression to devise estimates of DLT probability.

Version: 0.1.0
Imports: Iso
Published: 2018-09-28
DOI: 10.32614/CRAN.package.titeIR
Author: Lee McDaniel [aut, cre]
Maintainer: Lee McDaniel <lmcda4 at lsuhsc.edu>
License: GPL-3
NeedsCompilation: no
CRAN checks: titeIR results

Documentation:

Reference manual: titeIR.pdf

Downloads:

Package source: titeIR_0.1.0.tar.gz
Windows binaries: r-devel: titeIR_0.1.0.zip, r-release: titeIR_0.1.0.zip, r-oldrel: titeIR_0.1.0.zip
macOS binaries: r-release (arm64): titeIR_0.1.0.tgz, r-oldrel (arm64): titeIR_0.1.0.tgz, r-release (x86_64): titeIR_0.1.0.tgz, r-oldrel (x86_64): titeIR_0.1.0.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=titeIR to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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