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Performs comparative bioavailability calculations for Average Bioequivalence with Expanding Limits (ABEL). Implemented are 'Method A' / 'Method B' and the detection of outliers. If the design allows, assessment of the empiric Type I Error and iteratively adjusting alpha to control the consumer risk. Average Bioequivalence - optionally with a tighter (narrow therapeutic index drugs) or wider acceptance range (South Africa: Cmax) - is implemented as well.
Version: | 1.1.3 |
Depends: | R (≥ 3.5.0) |
Imports: | readxl (≥ 1.0.0), PowerTOST (≥ 1.5.3), lmerTest, nlme, pbkrtest, graphics, grDevices |
Suggests: | knitr, rmarkdown, testthat, devtools |
Published: | 2022-05-02 |
DOI: | 10.32614/CRAN.package.replicateBE |
Author: | Helmut Schütz [aut, cre], Michael Tomashevskiy [ctb], Detlew Labes [ctb] |
Maintainer: | Helmut Schütz <helmut.schuetz at bebac.at> |
BugReports: | https://github.com/Helmut01/replicateBE/issues |
License: | GPL (≥ 3) |
URL: | https://github.com/Helmut01/replicateBE |
NeedsCompilation: | no |
Materials: | README NEWS |
In views: | ClinicalTrials |
CRAN checks: | replicateBE results |
Reference manual: | replicateBE.pdf |
Vignettes: |
replicateBE |
Package source: | replicateBE_1.1.3.tar.gz |
Windows binaries: | r-devel: replicateBE_1.1.3.zip, r-release: replicateBE_1.1.3.zip, r-oldrel: replicateBE_1.1.3.zip |
macOS binaries: | r-release (arm64): replicateBE_1.1.3.tgz, r-oldrel (arm64): replicateBE_1.1.3.tgz, r-release (x86_64): replicateBE_1.1.3.tgz, r-oldrel (x86_64): replicateBE_1.1.3.tgz |
Old sources: | replicateBE archive |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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