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Optimize drug regimens through model-informed precision dosing, using individual pharmacokinetic (PK) and pharmacokinetic-pharmacodynamic (PK-PD) profiles. By integrating therapeutic drug monitoring (TDM) data with population models, 'posologyr' provides accurate posterior estimates and enables the calculation of personalized dosing regimens. The empirical Bayes estimates are computed following the method described by Kang et al. (2012) <doi:10.4196/kjpp.2012.16.2.97>.
Version: | 1.2.7 |
Depends: | R (≥ 3.5.0) |
Imports: | rxode2, stats, mvtnorm, data.table |
Suggests: | lotri, rmarkdown, testthat (≥ 3.0.0), ggplot2, magrittr, tidyr |
Published: | 2024-09-13 |
DOI: | 10.32614/CRAN.package.posologyr |
Author: | Cyril Leven [aut, cre, cph], Matthew Fidler [ctb], Emmanuelle Comets [ctb], Audrey Lavenu [ctb], Marc Lavielle [ctb] |
Maintainer: | Cyril Leven <cyril.leven at chu-brest.fr> |
BugReports: | https://github.com/levenc/posologyr/issues |
License: | AGPL-3 |
URL: | https://levenc.github.io/posologyr/, https://github.com/levenc/posologyr |
NeedsCompilation: | no |
Citation: | posologyr citation info |
Materials: | README NEWS |
In views: | Pharmacokinetics |
CRAN checks: | posologyr results |
Reference manual: | posologyr.pdf |
Package source: | posologyr_1.2.7.tar.gz |
Windows binaries: | r-devel: posologyr_1.2.7.zip, r-release: posologyr_1.2.7.zip, r-oldrel: posologyr_1.2.7.zip |
macOS binaries: | r-release (arm64): posologyr_1.2.7.tgz, r-oldrel (arm64): posologyr_1.2.7.tgz, r-release (x86_64): posologyr_1.2.7.tgz, r-oldrel (x86_64): posologyr_1.2.7.tgz |
Old sources: | posologyr archive |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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