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Pharmacometric Tools for Modeling & Simulation
Developed by Justin Wilkins, Bill Denney and Rik Schoemaker, with contributions from a host of others.
Pharmacometric tools for common data analytical tasks; closed-form solutions for calculating concentrations at given times after dosing based on compartmental PK models (1-compartment, 2-compartment and 3-compartment, covering infusions, zero- and first-order absorption, and lag times, after single doses and at steady state, per Bertrand & Mentre (2008) http://lixoft.com/wp-content/uploads/2016/03/PKPDlibrary.pdf); parametric simulation from NONMEM-generated parameter estimates and other output; and parsing, tabulating and plotting results generated by Perl-speaks-NONMEM (PsN).
To install:
devtools::install_github("kestrel99/pmxTools")or download directly from CRAN.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
Health stats visible at Monitor.