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metalite.ae: Adverse Events Analysis Using 'metalite'

Analyzes adverse events in clinical trials using the 'metalite' data structure. The package simplifies the workflow to create production-ready tables, listings, and figures discussed in the adverse events analysis chapters of "R for Clinical Study Reports and Submission" by Zhang et al. (2022) <https://r4csr.org/>.

Version: 0.1.4
Depends: R (≥ 4.1.0)
Imports: glue, metalite, r2rtf, stats, gt
Suggests: DescTools, covr, dplyr, knitr, forestly, reactable, rmarkdown, testthat (≥ 3.0.0), tibble, tidyr
Published: 2026-08-29
DOI: 10.32614/CRAN.package.metalite.ae
Author: Yilong Zhang [aut], Yujie Zhao [aut, cre], Hiroaki Fukuda [aut], Benjamin Wang [aut], Nan Xiao [aut], Sarad Nepal [aut], Madhusudhan Ginnaram [aut], Venkatesh Burla [ctb], Ruchitbhai Patel [aut], Brian Lang [aut], Xuan Deng [aut], Bing Liu [aut], Jeetender Chauhan [aut], Li Ma [ctb], Merck Sharp & Dohme Corp [cph]
Maintainer: Yujie Zhao <yujie.zhao at merck.com>
BugReports: https://github.com/Merck/metalite.ae/issues
License: GPL-3
URL: https://merck.github.io/metalite.ae/, https://github.com/Merck/metalite.ae
NeedsCompilation: no
Materials: README, NEWS
CRAN checks: metalite.ae results

Documentation:

Reference manual: metalite.ae.html , metalite.ae.pdf
Vignettes: Generate an Interactive AE Listing Table with reactable (source, R code)
Generate a Static AE Listing Table in RTF format (source, R code)
Generate Multiple AE Tables via 1 Single Metadata (source, R code)
Customize Columns in an AE Specific Table (source, R code)
Filter and Sort an AE Specific Table (source, R code)
Generate a Static AE-Specific Table in GT format (source, R code)
Generate a Static AE-Specific Table in RTF format (source, R code)
Subgroup Analysis for Specific AE (source, R code)
Customize Columns in an AE Summary Table (source, R code)
Generate a Static AE Summary Table in GT format (source, R code)
Create a AE Summary Mock-up Table (source, R code)
Generate a Static AE Summary Table in RTF format (source, R code)
Exposure Adjusted Event Rate (source, R code)
Introduction to metalite.ae (source, R code)
Unstratified and Stratified Miettinen and Nurminen Test (source, R code)

Downloads:

Package source: metalite.ae_0.1.4.tar.gz
Windows binaries: r-devel: metalite.ae_0.1.4.zip, r-release: metalite.ae_0.1.4.zip, r-oldrel: metalite.ae_0.1.4.zip
macOS binaries: r-release (arm64): metalite.ae_0.1.4.tgz, r-oldrel (arm64): metalite.ae_0.1.4.tgz, r-release (x86_64): metalite.ae_0.1.4.tgz, r-oldrel (x86_64): metalite.ae_0.1.4.tgz
Old sources: metalite.ae archive

Reverse dependencies:

Reverse imports: forestly, metalite.sl

Linking:

Please use the canonical form https://CRAN.R-project.org/package=metalite.ae to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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