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metabolic

Lifecycle: stable CRAN status R build status Monthly downloads badge Total downloads badge

The goal of metabolic is to provide all the data and the tools necessary to reproduce the meta-analysis published in Medicine & Science in Sports & Exercise.

Installation

You can install the released version of metabolic from CRAN with:

install.packages("metabolic")

You can install the development version of metabolic from from GitHub with:

# install.packages("remotes")
remotes::install_github("fmmattioni/metabolic")

Datasets

Dataset to reproduce meta-analyses

metabolic::metabolic_meta
#> # A tibble: 391 × 21
#>    study        endpoint population   age category_age duration category_durati…
#>    <chr>        <chr>    <fct>      <dbl> <fct>           <dbl> <fct>           
#>  1 Abdelbasset… BMI      T2D         54.6 > 50 y              8 5 - 10 weeks    
#>  2 Abdelbasset… HbA1c    T2D         54.6 > 50 y              8 5 - 10 weeks    
#>  3 Abdelbasset… HDL      T2D         54.6 > 50 y              8 5 - 10 weeks    
#>  4 Abdelbasset… HOMA-IR  T2D         54.6 > 50 y              8 5 - 10 weeks    
#>  5 Abdelbasset… LDL      T2D         54.6 > 50 y              8 5 - 10 weeks    
#>  6 Abdelbasset… Total C… T2D         54.6 > 50 y              8 5 - 10 weeks    
#>  7 Abdelbasset… Triglyc… T2D         54.6 > 50 y              8 5 - 10 weeks    
#>  8 Bækkerud 20… Body Ma… Overweigh…  40   30 - 50 y           6 5 - 10 weeks    
#>  9 Bækkerud 20… Flow-me… Overweigh…  40   30 - 50 y           6 5 - 10 weeks    
#> 10 Bækkerud 20… VO2max   Overweigh…  40   30 - 50 y           6 5 - 10 weeks    
#> # … with 381 more rows, and 14 more variables: men_ratio <dbl>,
#> #   category_men_ratio <fct>, type_exercise <chr>, bsln <dbl>,
#> #   bsln_adjusted <dbl>, category_bsln <fct>, N_HIIE <dbl>, Mean_HIIE <dbl>,
#> #   SD_HIIE <dbl>, N_MICT <dbl>, Mean_MICT <dbl>, SD_MICT <dbl>, HIIE <chr>,
#> #   desired_effect <chr>

Dataset to build the GOfER diagram

metabolic::metabolic_gofer
#> # A tibble: 115 × 33
#>    study groups sample_populati… sample_fitness sample_men_ratio anamnese_smoker
#>    <chr> <chr>  <chr>            <chr>                     <dbl> <chr>          
#>  1 Abde… HIIT   "T2D"            N/R                        0.63 N              
#>  2 Abde… MICT   "T2D"            N/R                        0.53 N              
#>  3 Bækk… HIIT   "Overweight\nOb… Sedentary                  0.41 N/R            
#>  4 Bækk… MICT   "Overweight\nOb… Sedentary                  0.41 N/R            
#>  5 Beet… HIIT   "Overweight\nOb… Active                     0.66 N/R            
#>  6 Beet… MICT   "Overweight\nOb… Active                     0.8  N/R            
#>  7 Burg… SIT    "Healthy"        Sedentary                  0.5  N/R            
#>  8 Burg… MICT   "Healthy"        Sedentary                  0.5  N/R            
#>  9 Ciol… HIIT   "Healthy"        Sedentary                  0    N              
#> 10 Ciol… MICT   "Healthy"        Sedentary                  0    N              
#> # … with 105 more rows, and 27 more variables:
#> #   anamnese_medicines_to_control_BP <chr>, age <dbl>,
#> #   design_type_of_exercise <chr>, design_sample_size <chr>,
#> #   design_training_duration <dbl>, design_training_frequency <chr>,
#> #   design_exercise_intensity <chr>, hiie_n_reps <chr>,
#> #   hiie_rep_duration <chr>, hiie_work_rest_ratio <chr>, compliance <dbl>,
#> #   endpoints_vo2max <chr>, endpoints_fmd <chr>, endpoints_body_mass <chr>, …

Reproduce meta-analysis for each clinical endpoint

library(metabolic)

perform_meta(endpoint = "VO2max")
#> ──────────────────────────  * VO2max meta-analysis *  ──────────────────────────
#> ✔ 'Overall'
#> ✔       └─ Performing meta-analysis
#> ✔       └─ Performing sensitivity analysis
#> ✔                └─ Meta-analysis results are robust! Keep going!
#> ✔ Performing meta-analysis and meta-regression on the Population subgroup
#> 
#> ✔ Performing meta-analysis and meta-regression on the Age subgroup
#> 
#> ✔ Performing meta-analysis and meta-regression on the Training Duration subgroup
#> 
#> ✔ Performing meta-analysis and meta-regression on the Men Ratio subgroup
#> 
#> ✔ Performing meta-analysis and meta-regression on the Type of Exercise subgroup
#> 
#> ✔ Performing meta-analysis and meta-regression on the Baseline subgroup
#> 
#> ✔ Performing meta-analysis and meta-regression on the Type of HIIE subgroup
#> 
#> ──────────────────────────────────  * DONE *  ──────────────────────────────────
#> # A tibble: 8 × 4
#>   subgroup          meta_analysis sensitivity_analysis meta_regression
#>   <chr>             <named list>  <named list>         <named list>   
#> 1 Overall           <metacont>    <metainf>            <lgl [1]>      
#> 2 Population        <metacont>    <lgl [1]>            <metareg>      
#> 3 Age               <metacont>    <lgl [1]>            <metareg>      
#> 4 Training Duration <metacont>    <lgl [1]>            <metareg>      
#> 5 Men Ratio         <metacont>    <lgl [1]>            <metareg>      
#> 6 Type of Exercise  <metacont>    <lgl [1]>            <metareg>      
#> 7 Baseline Values   <metacont>    <lgl [1]>            <metareg>      
#> 8 Type of HIIE      <metacont>    <lgl [1]>            <metareg>

Build a GOfER (Graphical Overview for Evidence Reviews) diagram

Citation

citation("metabolic")
#> 
#> To cite metabolic in publications use:
#> 
#> Maturana M, Felipe, Martus, Peter, Zipfel, Stephan, Nieß, M A (2020).
#> "Effectiveness of HIIE versus MICT in Improving Cardiometabolic Risk
#> Factors in Health and Disease: a meta-anaylsis." _Medicine & Science in
#> Sports & Exercise_, *Published Ahead of Print*. doi:
#> 10.1249/MSS.0000000000002506 (URL:
#> https://doi.org/10.1249/MSS.0000000000002506), <URL:
#> https://journals.lww.com/acsm-msse/Abstract/9000/Effectiveness_of_HIIE_versus_MICT_in_Improving.96194.aspx>.
#> 
#> A BibTeX entry for LaTeX users is
#> 
#>   @Article{,
#>     title = {Effectiveness of HIIE versus MICT in Improving Cardiometabolic Risk Factors in Health and Disease: a meta-anaylsis},
#>     author = {Mattioni Maturana and {Felipe} and {Martus} and {Peter} and {Zipfel} and {Stephan} and {Nieß} and Andreas M},
#>     journal = {Medicine & Science in Sports & Exercise},
#>     volume = {Published Ahead of Print},
#>     year = {2020},
#>     url = {https://journals.lww.com/acsm-msse/Abstract/9000/Effectiveness_of_HIIE_versus_MICT_in_Improving.96194.aspx},
#>     doi = {10.1249/MSS.0000000000002506},
#>   }

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
Health stats visible at Monitor.