The hardware and bandwidth for this mirror is donated by dogado GmbH, the Webhosting and Full Service-Cloud Provider. Check out our Wordpress Tutorial.
If you wish to report a bug, or if you are interested in having us mirror your free-software or open-source project, please feel free to contact us at mirror[@]dogado.de.
An R package for generating concentration-time profiles from linear pharmacokinetic (PK) systems.
To install from CRAN:
install.packages("linpk")To install the latest development version directly from GitHub:
require(devtools)
devtools::install_github("benjaminrich/linpk")To simulate a PK profile from a one-compartment model with first-order absorption under repeated dosing:
t.obs <- seq(0, 6*24, 0.5)
y <- pkprofile(t.obs, cl=0.5, vc=11, ka=1.3, dose=list(amt=100, addl=9, ii=12))
plot(y)
For a more detailed introduction to the package, see the vignette.
There is a companion shiny app that provides a demo of the package capabilities, and also generates code that can be placed in an R script. It can be accessed at https://benjaminrich.shinyapps.io/linpk-demo-app/ or run locally by pasting the following lines in an R console:
# Make sure the required packages are installed (if not, install them)
sapply(c("shiny", "shinyjs", "shinyAce", "dygraphs", "linpk"), requireNamespace)
linpk::linpkApp()The app will open in a browser, and looks like this:
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
Health stats visible at Monitor.