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ivdtools: Statistical Tools for Evaluation of in Vitro Diagnostic Reagents

Provides statistical workflows used in the evaluation of in vitro diagnostic reagents. Facilities include method comparison, commutability assessment, Bland-Altman and receiver operating characteristic analysis, qualitative agreement, C5 and C95 estimation, precision and variance-component analysis, linearity, interference, dilution and spiking studies, high-dose hook assessment, measurement uncertainty, reference-material bias, reference intervals, stability studies, quality-control charts, curve fitting, analytical sensitivity, outlier and normality assessment, and sample-size calculations. For methodological details, see Bland and Altman (1986) <doi:10.1016/S0140-6736(86)90837-8>, Passing and Bablok (1983) <doi:10.1515/cclm.1983.21.11.709>, Linnet (1993) <doi:10.1093/clinchem/39.3.424>, Hawkins and Kraker (2026) <doi:10.1093/jalm/jfaf183>, Hanley and McNeil (1982) <doi:10.1148/radiology.143.1.7063747>, Horn et al. (1998) <doi:10.1093/clinchem/44.3.622>, Westgard et al. (1981) <doi:10.1093/clinchem/27.3.493>, and Lu et al. (2016) <doi:10.1515/ijb-2015-0039>.

Version: 0.2.5
Depends: R (≥ 4.1.0)
Imports: ggplot2, ggrepel, minpack.lm, nloptr, nls2, nortest, ppwdeming, rlang, stats, utils, VCA, VFP
Suggests: knitr, rmarkdown, testthat (≥ 3.0.0)
Published: 2026-09-11
DOI: 10.32614/CRAN.package.ivdtools
Author: hiox-tech [cph, aut, cre]
Maintainer: hiox-tech <GeorgeBinDragon at outlook.com>
BugReports: https://github.com/hiox-tech/ivdtools/issues
License: MIT + file LICENSE
URL: https://github.com/hiox-tech/ivdtools
NeedsCompilation: no
Materials: NEWS
CRAN checks: ivdtools results

Documentation:

Reference manual: ivdtools.html , ivdtools.pdf
Vignettes: Introduction to ivdtools (source, R code)

Downloads:

Package source: ivdtools_0.2.5.tar.gz
Windows binaries: r-devel: ivdtools_0.1.3.zip, r-release: ivdtools_0.1.3.zip, r-oldrel: ivdtools_0.2.5.zip
macOS binaries: r-release (arm64): ivdtools_0.1.3.tgz, r-oldrel (arm64): ivdtools_0.2.5.tgz, r-release (x86_64): ivdtools_0.2.5.tgz, r-oldrel (x86_64): ivdtools_0.2.5.tgz
Old sources: ivdtools archive

Linking:

Please use the canonical form https://CRAN.R-project.org/package=ivdtools to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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