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iAdapt: Two-Stage Adaptive Dose-Finding Clinical Trial Design

Simulate and implement early phase two-stage adaptive dose-finding design for binary and quasi-continuous toxicity endpoints. See Chiuzan et al. (2018) for further reading <doi:10.1080/19466315.2018.1462727>.

Version: 2.0.1
Depends: R (≥ 3.5.0), shiny, shinydashboard
Imports: Matrix, grDevices, utils
Suggests: knitr, rmarkdown
Published: 2021-08-06
DOI: 10.32614/CRAN.package.iAdapt
Author: Alyssa Vanderbeek [aut, cre], Laura Cosgrove [ctb], Elizabeth Garrett-Mayer [ctb], Cody Chiuzan [ctb]
Maintainer: Alyssa Vanderbeek <vanderbeekam at gmail.com>
License: LGPL-3
NeedsCompilation: no
Materials: README
CRAN checks: iAdapt results

Documentation:

Reference manual: iAdapt.pdf
Vignettes: Trial simulation with binary toxicity measure
Trial implementation
Trial simulation with quasi-continuous toxicity measure

Downloads:

Package source: iAdapt_2.0.1.tar.gz
Windows binaries: r-devel: iAdapt_2.0.1.zip, r-release: iAdapt_2.0.1.zip, r-oldrel: iAdapt_2.0.1.zip
macOS binaries: r-release (arm64): iAdapt_2.0.1.tgz, r-oldrel (arm64): iAdapt_2.0.1.tgz, r-release (x86_64): iAdapt_2.0.1.tgz, r-oldrel (x86_64): iAdapt_2.0.1.tgz
Old sources: iAdapt archive

Linking:

Please use the canonical form https://CRAN.R-project.org/package=iAdapt to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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