The hardware and bandwidth for this mirror is donated by dogado GmbH, the Webhosting and Full Service-Cloud Provider. Check out our Wordpress Tutorial.
If you wish to report a bug, or if you are interested in having us mirror your free-software or open-source project, please feel free to contact us at mirror[@]dogado.de.
A streamlined tool for eplet analysis of donor and recipient HLA (human leukocyte antigen) mismatch. Messy, low-resolution HLA typing data is cleaned, and imputed to high-resolution using the NMDP (National Marrow Donor Program) haplotype reference database <https://haplostats.org/haplostats>. High resolution data is analyzed for overall or single antigen eplet mismatch using a reference table (currently supporting 'HLAMatchMaker' <http://www.epitopes.net> versions 2 and 3). Data can enter or exit the workflow at different points depending on the user's aims and initial data quality.
| Version: | 1.0.0 |
| Depends: | R (≥ 4.1.0) |
| Imports: | devtools, tidyverse, dplyr, reshape2, schoolmath, tibble, tidyselect, stringr, purrr, tidyr, utils, readr, janitor |
| Suggests: | knitr, rmarkdown |
| Published: | 2023-01-31 |
| Author: | Joan Zhang [aut, cre], Aileen Johnson [aut], Christian P Larsen [cph, aut] |
| Maintainer: | Joan Zhang <joan.zhang at emory.edu> |
| BugReports: | https://github.com/LarsenLab/hlaR/issues |
| License: | MIT + file LICENSE |
| URL: | https://pubmed.ncbi.nlm.nih.gov/35101308/, https://emory-larsenlab.shinyapps.io/hlar_shiny/ |
| NeedsCompilation: | no |
| CRAN checks: | hlaR results |
| Reference manual: | hlaR.pdf |
| Vignettes: |
Imputation Eplet Mismatch |
| Package source: | hlaR_1.0.0.tar.gz |
| Windows binaries: | r-devel: hlaR_1.0.0.zip, r-release: hlaR_1.0.0.zip, r-oldrel: hlaR_1.0.0.zip |
| macOS binaries: | r-release (arm64): hlaR_1.0.0.tgz, r-oldrel (arm64): hlaR_1.0.0.tgz, r-release (x86_64): hlaR_1.0.0.tgz, r-oldrel (x86_64): hlaR_1.0.0.tgz |
| Old sources: | hlaR archive |
Please use the canonical form https://CRAN.R-project.org/package=hlaR to link to this page.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
Health stats visible at Monitor.