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hacksig: A Tidy Framework to Hack Gene Expression Signatures

A collection of cancer transcriptomics gene signatures as well as a simple and tidy interface to compute single sample enrichment scores either with the original procedure or with three alternatives: the "combined z-score" of Lee et al. (2008) <doi:10.1371/journal.pcbi.1000217>, the "single sample GSEA" of Barbie et al. (2009) <doi:10.1038/nature08460> and the "singscore" of Foroutan et al. (2018) <doi:10.1186/s12859-018-2435-4>. The 'get_sig_info()' function can be used to retrieve information about each signature implemented.

Version: 0.1.2
Depends: R (≥ 4.0)
Imports: dplyr (≥ 1.0.7), future.apply (≥ 1.8.1), rlang (≥ 0.4.11), stats (≥ 4.0.5), tibble (≥ 3.1.5), tidyr (≥ 1.1.4)
Suggests: covr, future (≥ 1.22.1), ggplot2 (≥ 3.3.5), knitr (≥ 1.36), msigdbr (≥ 7.4.1), purrr (≥ 0.3.4), rmarkdown (≥ 2.11)
Published: 2022-02-17
DOI: 10.32614/CRAN.package.hacksig
Author: Andrea Carenzo ORCID iD [aut, cre], Loris De Cecco ORCID iD [aut], Federico Pistore [aut]
Maintainer: Andrea Carenzo <andrea.carenzo at gmail.com>
BugReports: https://github.com/Acare/hacksig/issues
License: MIT + file LICENSE
URL: https://github.com/Acare/hacksig
NeedsCompilation: no
Materials: README NEWS
CRAN checks: hacksig results

Documentation:

Reference manual: hacksig.pdf
Vignettes: Introduction to hacksig

Downloads:

Package source: hacksig_0.1.2.tar.gz
Windows binaries: r-devel: hacksig_0.1.2.zip, r-release: hacksig_0.1.2.zip, r-oldrel: hacksig_0.1.2.zip
macOS binaries: r-release (arm64): hacksig_0.1.2.tgz, r-oldrel (arm64): hacksig_0.1.2.tgz, r-release (x86_64): hacksig_0.1.2.tgz, r-oldrel (x86_64): hacksig_0.1.2.tgz
Old sources: hacksig archive

Linking:

Please use the canonical form https://CRAN.R-project.org/package=hacksig to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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