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fcfdr: Flexible cFDR

Provides functions to implement the Flexible cFDR (Hutchinson et al. (2021) <doi:10.1371/journal.pgen.1009853>) and Binary cFDR (Hutchinson et al. (2021) <doi:10.1101/2021.10.21.465274>) methodologies to leverage auxiliary data from arbitrary distributions, for example functional genomic data, with GWAS p-values to generate re-weighted p-values.

Version: 1.0.0
Depends: R (≥ 3.5.0)
Imports: locfdr, MASS, ggplot2, cowplot, fields, dplyr, spatstat.geom, polyCub, hexbin, bigsplines, data.table, grDevices, Hmisc
Suggests: stats, knitr, rmarkdown, digest, testthat (≥ 3.0.0)
Published: 2022-02-07
DOI: 10.32614/CRAN.package.fcfdr
Author: Anna Hutchinson ORCID iD [aut, cre], Chris Wallace [aut], Thomas Willis [ctb, aut], James Liley [ctb]
Maintainer: Anna Hutchinson <annahutchinson1995 at gmail.com>
License: MIT + file LICENSE
NeedsCompilation: no
Materials: README NEWS
CRAN checks: fcfdr results

Documentation:

Reference manual: fcfdr.pdf
Vignettes: Extra Information
Introductory vignette
LDAK vignette
T1D Application

Downloads:

Package source: fcfdr_1.0.0.tar.gz
Windows binaries: r-devel: fcfdr_1.0.0.zip, r-release: fcfdr_1.0.0.zip, r-oldrel: fcfdr_1.0.0.zip
macOS binaries: r-release (arm64): fcfdr_1.0.0.tgz, r-oldrel (arm64): fcfdr_1.0.0.tgz, r-release (x86_64): fcfdr_1.0.0.tgz, r-oldrel (x86_64): fcfdr_1.0.0.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=fcfdr to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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