The hardware and bandwidth for this mirror is donated by dogado GmbH, the Webhosting and Full Service-Cloud Provider. Check out our Wordpress Tutorial.
If you wish to report a bug, or if you are interested in having us mirror your free-software or open-source project, please feel free to contact us at mirror[@]dogado.de.

exeval: An R-package for External Evaluation of popPKPD Models.

exeval provides a reproducible workflow for external evaluation of population pharmacokinetic (popPK) and pharmacokinetic-pharmacodynamic (PKPD) models using independent validation datasets. MAP estimation is currently powered by mapbayr.

The package supports model-informed evaluation workflows based on:

• Maximum a posteriori (MAP) estimation via mapbayr
• posterior model updating
• a priori and Bayesian forecasting simulations
• predictive performance metrics
• model comparison across candidate models
• graphical diagnostics and fit screening

Models can be supplied as:

• mrgsolve model code (mrgsolve)
• compiled mrgmod objects
• built-in curated models included in exeval

Input datasets should follow standard pharmacometric event-table structure (e.g. ID, TIME, DV, AMT, EVID, CMT, OCC), with helper functions available for data preparation.

Installation

You can install the development version of exeval from GitHub with:

install.packages("devtools")
devtools::install_github("Martin-Umpierrez/exeval")

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
Health stats visible at Monitor.