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Release Notes

drda 2.0.4

drda 2.0.3

drda 2.0.2

drda 2.0.1

drda 2.0.0

It is now possible to fit models using either the log-dose or the dose scale.

To accommodate this extension it was necessary to change the default model parameterization, which now follows that of the Emax model (Macdougall, 2006).

Briefly, the 5-parameter logistic function is now defined as

alpha + delta / (1 + nu * exp(-eta * (x - phi)))^(1 / nu)

Parameter alpha is the value of the function when x approaches -Inf. Parameter delta is the (signed) height of the curve. Parameter eta > 0 represents the steepness (growth rate) of the curve. Parameter phi is related to the mid-value of the function. Parameter nu affects near which asymptote maximum growth occurs.

Similarly, the newly implemented log-logistic function (when x >= 0) is defined as

alpha + delta * (x^eta / (x^eta + nu * phi^eta))^(1 / nu)

Check the vignette (vignette("drda", package = "drda")) or the help page (help(drda)) to know more about the available models.

Here is a change log from previous version:

drda 1.0.0

First public release.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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