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Type: Package
Title: Cystic Fibrosis Survival Prediction Model Based on Stanojevic Model
Version: 0.3.0
Maintainer: Amin Adibi <adibi@alumni.ubc.ca>
Description: Allows clinicians to predict survival probabilities over the next two years for cystic fibrosis patients, based on the clinical prediction models published in Stanojevic et al. (2019) <doi:10.1183/13993003.00224-2019>.
License: GPL-3
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.1.0
NeedsCompilation: no
Packaged: 2020-05-05 00:46:47 UTC; maadibi
Author: Sanja Stanojevic [aut, cph], Jenna Sykes [aut, cph], George A. Whitmore [aut, cph], Shawn D. Aaron [aut, cph], Aida Kazemi [aut], Amin Adibi [aut, cre]
Repository: CRAN
Date/Publication: 2020-05-07 10:00:06 UTC

Predicts 1- and 2- year Mortality Prediction Models in Cystic Fibrosis (CF)

Description

Predicts 1- and 2- year Mortality Prediction Models in Cystic Fibrosis (CF)

Usage

predictcfmortality(
  age,
  male,
  fvc,
  fev1,
  fev1LastYear,
  bcepacia,
  underweight,
  nHosp,
  pancreaticInsufficient,
  CFRelatedDiabetes,
  ageAtDiagnosis
)

Arguments

age

Patient age, in years

male

A binary variable with 0 for females and 1 for males

fvc

FVC percent predicted in the current year (0-150)

fev1

FEV1 percent predicted in the current year (0-150)

fev1LastYear

FEV1 percent predicted in the preceding year (0-150)

bcepacia

A binary with 0 for no B. cepacia complex and 1 for B. cepacia complex

underweight

A binary with 1 for underweight (BMI < 18.5 if age >= 19 or BMI percentile <= 12% if age < 19)

nHosp

An integer number of hospitalizations in preceding year

pancreaticInsufficient

A binary taking 1 for pancreatic insufficient status and 0 otherwise

CFRelatedDiabetes

A binary variable for CF related diabetes

ageAtDiagnosis

A number for age at CF diagnosis in years

Value

1- and 2-year predicted mortality risk

Source

https://erj.ersjournals.com/content/early/2019/05/08/13993003.00224-2019

Examples

predictcfmortality (age = 16, male = 0, fvc = 66.7, fev1 = 47.4, fev1LastYear = 80.5, 
                    bcepacia = 0, underweight = 0, nHosp = 0, pancreaticInsufficient = 1, 
                    CFRelatedDiabetes = 0, ageAtDiagnosis = 0.9)
predictcfmortality (age = 40.4, male = 1, fvc = 25.7, fev1 = 19.2, fev1LastYear = 20, 
                    bcepacia = 1, underweight = 1, nHosp = 6, pancreaticInsufficient = 0, 
                    CFRelatedDiabetes = 0, ageAtDiagnosis = 27.2)
predictcfmortality (age = 44, male = 1, fvc = 72.95, fev1 = 55.5, fev1LastYear = 52.5, 
                    bcepacia = 0, underweight = 1, nHosp = 0, pancreaticInsufficient = 0, 
                    CFRelatedDiabetes = 0, ageAtDiagnosis = 29)

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
Health stats visible at Monitor.